Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings
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Anti-Cancer Properties of the Naturally Occurring Aphrodisiacs: Icariin and Its DerivativesA novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cellsCytotoxic effect of icaritin and its mechanisms in inducing apoptosis in human burkitt lymphoma cell line.Identification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CELIcaritin synergistically enhances the radiosensitivity of 4T1 breast cancer cells.Icaritin inhibits JAK/STAT3 signaling and growth of renal cell carcinoma.Spred2 modulates the erythroid differentiation induced by imatinib in chronic myeloid leukemia cellsIcaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma.Anticancer effect of icaritin on human lung cancer cells through inducing S phase cell cycle arrest and apoptosis.Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3.A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway.Icaritin suppresses the proliferation of human osteosarcoma cells in vitro by increasing apoptosis and decreasing MMP expression.Icaritin enhances mESC self-renewal through upregulating core pluripotency transcription factors mediated by ERα.Icaritin Reduces Oral Squamous Cell Carcinoma Progression via the Inhibition of STAT3 Signaling.Chemical Constituents, Quality Control, and Bioactivity of Epimedii Folium (Yinyanghuo).Expression and functions of the STAT3-SCLIP pathway in chronic myeloid leukemia cellsIcaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways.Targeting BCR-ABL+ stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex.Role of STAT3 in Transformation and Drug Resistance in CMLEstablished Human Cell Lines as Models to Study Anti-leukemic Effects of Flavonoids.Iciartin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signaling.Improvement of icaritin on hematopoietic function in cyclophosphamide-induced myelosuppression mice.Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies.The hydrolysed products of iridoid glycosides can enhance imatinib mesylate-induced apoptosis in human myeloid leukaemia cells.
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P2860
Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings
description
2011 nî lūn-bûn
@nan
2011 թուականին հրատարակուած գիտական յօդուած
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2011 թվականին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@ast
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@en
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@nl
type
label
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@ast
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@en
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@nl
prefLabel
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@ast
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@en
Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@nl
P2093
P2860
P3181
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Icaritin shows potent anti-leu ...... and JAK2/STAT3 /AKT signalings
@en
P2093
Chong wen Dai
Fan jie Gong
Guang sen Zhang
Hong ling Peng
Jian Kai Shen
Jian feng Zhu
Rui juan Li
Su fang Liu
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P304
P3181
P356
10.1371/JOURNAL.PONE.0023720
P407
P577
2011-01-01T00:00:00Z