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P184
Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text miningEvaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytesAflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinomaFrom the exposome to mechanistic understanding of chemical-induced adverse effectsThe exposome concept in a human nutrigenomics study: evaluating the impact of exposure to a complex mixture of phytochemicals using transcriptomics signaturesToward interoperable bioscience dataRisk assessment of endogenous formation of carcinogenic N-nitroso compounds in response to intake of NO-aspirinHigh-throughput data integration of RNA-miRNA-circRNA reveals novel insights into mechanisms of benzo[a]pyrene-induced carcinogenicityNew insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesisBiotransformation pathway maps in WikiPathways enable direct visualization of drug metabolism related expression changesComparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundanceTranscriptomic and metabolomic data integration.An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms.Newborn sex-specific transcriptome signatures and gestational exposure to fine particles: findings from the ENVIRONAGE birth cohort.Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.RNA-Seq provides new insights in the transcriptome responses induced by the carcinogen benzo[a]pyrene.Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines.Bioavailability of soil-adsorbed cadmium in orally exposed male rats.Possible relevance of pigeons as an indicator species for monitoring air pollution.Human respiratory disease: environmental carcinogens and lung cancer risk.Volatile N-nitrosamine formation after intake of nitrate at the ADI level in combination with an amine-rich diet.DTW4Omics: comparing patterns in biological time seriesHuman health risk assessment: A case study involving heavy metal soil contamination after the flooding of the river Meuse during the winter of 1993-1994.Human health risk assessment in relation to environmental pollution of two artificial freshwater lakes in The Netherlands.Does the risk of childhood diabetes mellitus require revision of the guideline values for nitrate in drinking water?ToxDB: pathway-level interpretation of drug-treatment dataToxicogenomic profiles in relation to maternal immunotoxic exposure and immune functionality in newborns.The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays.Biological marks of early-life socioeconomic experience is detected in the adult inflammatory transcriptome.A dictionary to identify small molecules and drugs in free text.Transcriptome-wide analyses indicate mitochondrial responses to particulate air pollution exposure.Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicityTranscriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.Use of crayfish in biomonitoring studies of environmental pollution of the river Meuse.Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling.
P50
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P50
description
Professor at Maastricht University
@en
onderzoeker
@nl
name
Jos Kleinjans
@ast
Jos Kleinjans
@en
Jos Kleinjans
@es
Jos Kleinjans
@nl
Jos Kleinjans
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type
label
Jos Kleinjans
@ast
Jos Kleinjans
@en
Jos Kleinjans
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Jos Kleinjans
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Jos Kleinjans
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altLabel
J C Kleinjans
@en
J. Kleinjans
@nl
J.C.S. Kleinjans
@en
J.C.S. Kleinjans
@nl
Jos C.S. Kleinjans
@en
Joseph Catharina Stephanus Kleinjans
@en
Joseph Catharina Stephanus Kleinjans
@nl
Kleinjans JC
@en
prefLabel
Jos Kleinjans
@ast
Jos Kleinjans
@en
Jos Kleinjans
@es
Jos Kleinjans
@nl
Jos Kleinjans
@sl
P1006
P214
P1006
P185
P19
P21
P214
P2456
P31
P569
1954-09-02T00:00:00Z
P735
P7859
lccn-n2014186566