Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010. - Wikidata - wikimedia - TriplyDB

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

http://www.wikidata.org/entity/Q34181630

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Animal-Free Chemical Safety Assessment Novel in vitro and mathematical models for the prediction of chemical toxicity Insulin resistance and environmental pollutants: experimental evidence and future perspectives Drug Metabolism - From In Vitro to In Vivo, From Simple to Complex: Reflections of the BCPT Nordic Prize 2014 Awardee Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data CERAPP: Collaborative Estrogen Receptor Activity Prediction Project Supporting read-across using biological data Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests.Analysis of publically available skin sensitization data from REACH registrations 2008-2014 Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.Systems biology modeling of omics data: effect of cyclosporine a on the Nrf2 pathway in human renal cells Anchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing data.Skin sensitization: Implications for integration of clinical data into hazard identification and risk assessment.Accounting for data variability, a key factor in in vivo/in vitro relationships: application to the skin sensitization potency (in vivo LLNA versus in vitro DPRA) example.Development of a Test Method for the Evaluation of DNA Damage in Mouse Spermatogonial Stem Cells Stem cell proliferation patterns as an alternative for in vivo prediction and discrimination of carcinogenic compounds.Characterization of a human skin equivalent model to study the effects of ultraviolet B radiation on keratinocytes.Screening of repeated dose toxicity data present in SCC(NF)P/SCCS safety evaluations of cosmetic ingredients.Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and structure-based virtual screening approaches.The usefulness of systematic reviews of animal experiments for the design of preclinical and clinical studies.In silico toxicology - non-testing methods.Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery Chemical safety without animals.Mechanism of regulation of stem cell differentiation by matrix stiffness.Biomimetic tissues on a chip for drug discovery.Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library.QSAR models of human data can enrich or replace LLNA testing for human skin sensitization.Wind of change challenges toxicological regulators.Probabilistic hazard assessment for skin sensitization potency by dose-response modeling using feature elimination instead of quantitative structure-activity relationships.Key messages of recent publications in the field of toxicology.Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells.Application of Gut Cell Models for Toxicological and Bioactivity Studies of Functional and Novel Foods.Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells.Immunotoxicant screening and prioritization in the twenty-first century.Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation.Non-animal test methods for predicting skin sensitization potentials.Skeletal muscle-derived cell cultures as potent models in regenerative medicine research.

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Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

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Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

Rapid and simple kinetics screening assay for electrophilic dermal sensitizers using nitrobenzenethiol

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

A new view of carcinogenesis and an alternative approach to cancer therapy

Discriminating different classes of toxicants by transcript profiling

The role of transgenic mouse models in carcinogen identification

IPCS framework for analyzing the relevance of a noncancer mode of action for humans

Toxicity testing in the 21st century: a vision and a strategy

Rat toxicogenomic study reveals analytical consistency across microarray platforms

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

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