Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy
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Neuronal Mitophagy in Neurodegenerative DiseasesA novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia ContinuumMolecular definitions of autophagy and related processes.New methods for monitoring mitochondrial biogenesis and mitophagy in vitro and in vivo.Mitophagy in neurodegeneration and aging.Expanding perspectives on the significance of mitophagy in cancer.Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis.Major review: Molecular genetics of primary open-angle glaucoma.Autophagy in neurodegenerative diseases: pathogenesis and therapy.Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway?Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand.Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular FunctionAMPK: guardian of metabolism and mitochondrial homeostasis.Mitophagy as a Protective Mechanism against Myocardial Stress.Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein.Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.Autophagy balances inflammation in innate immunity.Causative Genes in Amyotrophic Lateral Sclerosis and Protein Degradation Pathways: a Link to Neurodegeneration.Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria.A Molecular Approach to Mitophagy and Mitochondrial Dynamics.Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights.Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy.TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity.The TBK1-OPTN Axis Mediates Crosstalk Between Mitophagy and the Innate Immune Response: A Potential Therapeutic Target for Neurodegenerative Diseases.Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy.Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma.Altered Functions and Interactions of Glaucoma-Associated Mutants of Optineurin.The Role of Mitophagy in Innate Immunity.Autophagy in Age-Associated Neurodegeneration.Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.Common Traits Spark the Mitophagy/Xenophagy Interplay
P2860
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P2860
Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Dynamic recruitment and activa ...... quired for efficient mitophagy
@ast
Dynamic recruitment and activa ...... quired for efficient mitophagy
@en
type
label
Dynamic recruitment and activa ...... quired for efficient mitophagy
@ast
Dynamic recruitment and activa ...... quired for efficient mitophagy
@en
prefLabel
Dynamic recruitment and activa ...... quired for efficient mitophagy
@ast
Dynamic recruitment and activa ...... quired for efficient mitophagy
@en
P2860
P356
P1476
Dynamic recruitment and activa ...... quired for efficient mitophagy
@en
P2093
Andrew S Moore
Erika L F Holzbaur
P2860
P304
P356
10.1073/PNAS.1523810113
P407
P577
2016-06-14T00:00:00Z