about
Induction of ErbB-3 expression by alpha6beta4 integrin contributes to tamoxifen resistance in ERbeta1-negative breast carcinomasMDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosisGain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulationTranscriptional regulation of hypoxia-inducible factor 1alpha by HIPK2 suggests a novel mechanism to restrain tumor growthMDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathwayHIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic functionMDMX stability is regulated by p53-induced caspase cleavage in NIH3T3 mouse fibroblastsTargeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha
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onderzoeker
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Ada Sacchi
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Ada Sacchi
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Ada Sacchi
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