The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode
about
Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity.Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase ITopoisomerase inhibitors as anticancer agents: a patent update.Design, Synthesis and Cytotoxicity Evaluation of New 2-Aryl-5, 6-Dihydropyrrolo[2, 1-a]Isoquinoline Derivatives as Topoisomerase Inhibitors.Analogue-based approaches in anti-cancer compound modelling: the relevance of QSAR models.An Unprecedented Straightforward Synthesis of Chiral Pyrrolo[3,4-b]quinolone and Pyrrolo[3,2-b]quinolone Backbones Starting fromtrans-4-Hydroxy-L-prolineImidazoles as potential anticancer agents
P2860
Q35152039-CB1331A1-EBF5-491B-A62B-F9329F4033B1Q36525254-250D817C-D484-4162-A70E-152949C875B3Q38101143-6C04F3D4-651E-4223-8839-4E2D97291DD1Q38627884-D6C7A5D7-4EE6-42C1-AE88-39757C3CC93CQ41104504-A8AC11EF-0035-4F74-8800-0453FB971C95Q59125401-F9AD9970-7DA1-4A81-9833-7490A0CF3E14Q59149996-868CA423-7954-4BE2-ACB1-1C879BF1E550
P2860
The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The structure–activity relatio ...... camptothecin-like binding mode
@ast
The structure–activity relatio ...... camptothecin-like binding mode
@en
type
label
The structure–activity relatio ...... camptothecin-like binding mode
@ast
The structure–activity relatio ...... camptothecin-like binding mode
@en
prefLabel
The structure–activity relatio ...... camptothecin-like binding mode
@ast
The structure–activity relatio ...... camptothecin-like binding mode
@en
P2093
P2860
P1476
The structure–activity relatio ...... camptothecin-like binding mode
@en
P2093
Andrew E. Morrell
Keli Agama
Maris A. Cinelli
Mark Cushman
Surbhi Agrawal
Thomas S. Dexheimer
P2860
P304
P356
10.1016/J.BMC.2010.06.040
P407
P50
P577
2010-08-01T00:00:00Z