Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
about
Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumorsTelomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksInvolvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindleReconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNAPhosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint responseHus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damageAn N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing.Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeChl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathwayLoss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damageThe Schizosaccharomyces pombe rad3 checkpoint geneChk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpointS-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombeChk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS responseA human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damageATM binds to beta-adaptin in cytoplasmic vesiclesSaccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptorLimited TTP supply affects telomere length regulation in a telomerase-independent fashionDNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.Inhibition of proteasomal degradation of rpn4 impairs nonhomologous end-joining repair of DNA double-strand breaks.Rfc5, in cooperation with rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae.Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae.Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae.The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency.Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae.Protein phosphatases pph3, ptc2, and ptc3 play redundant roles in DNA double-strand break repair by homologous recombination.The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae.RAD9 and RAD24 define two additive, interacting branches of the DNA damage checkpoint pathway in budding yeast normally required for Rad53 modification and activationMec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p.Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathwayIdentification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiaeInvolvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiaeThe SFP1 gene product of Saccharomyces cerevisiae regulates G2/M transitions during the mitotic cell cycle and DNA-damage responseA role for the replication proteins PCNA, RF-C, polymerase epsilon and Cdc45 in transcriptional silencing in Saccharomyces cerevisiaeThe role of Stn1p in Saccharomyces cerevisiae telomere capping can be separated from its interaction with Cdc13p.
P2860
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P2860
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@ast
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@en
type
label
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@ast
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@en
prefLabel
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@ast
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@en
P2093
P3181
P1433
P1476
Regulation of RAD53 by the ATM ...... cell cycle checkpoint pathways
@en
P2093
P304
P3181
P356
10.1126/SCIENCE.271.5247.357
P407
P577
1996-01-19T00:00:00Z