Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
about
Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressureAssociation of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progressionp27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathwayBone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6Antitumour effect of cyclin-dependent kinase inhibitors (p16(INK4A), p18(INK4C), p19(INK4D), p21(WAF1/CIP1) and p27(KIP1)) on malignant glioma cellsDysregulation of HSG triggers vascular proliferative disordersRegulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouseCHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirusRole of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.Altered p27(Kip1) phosphorylation, localization, and function in human epithelial cells resistant to transforming growth factor beta-mediated G(1) arrestRapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence.Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient miceEvidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cellsEarly embryonic death in mice lacking the beta-catenin-binding protein DuplinTransforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsGene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti.Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinasesDifferential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesisTransforming growth factor-beta, transforming growth factor-beta receptor II, and p27Kip1 expression in nontumorous and neoplastic human pituitariesGerm-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humansRole of Plk2 (Snk) in mouse development and cell proliferationPten dose dictates cancer progression in the prostateThe major transcription initiation site of the p27Kip1 gene is conserved in human and mouse and produces a long 5'-UTRTransforming growth factor-beta and breast cancer: Cell cycle arrest by transforming growth factor-beta and its disruption in cancerThe role of the ubiquitination-proteasome pathway in breast cancer: use of mouse models for analyzing ubiquitination processesReduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cellsMouse Models in Prostate Cancer Translational Research: From Xenograft to PDXChanges in primary lymphoid organs with agingOrchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingGenetically engineered mouse models of prostate cancerEZH2 is highly expressed in pituitary adenomas and associated with proliferationTherapeutic targeting of the cyclin D3:CDK4/6 complex in T cell leukemia.Mislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapyFOXO3a/p27kip1 expression and essential role after acute spinal cord injury in adult rat.Stabilization of MyoD by direct binding to p57(Kip2)The INK4 family of cell cycle inhibitors in cancer
P2860
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P2860
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@ast
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@en
type
label
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@ast
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@en
prefLabel
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@ast
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@en
P2093
P3181
P1433
P1476
Mice lacking p27(Kip1) display ...... ysplasia, and pituitary tumors
@en
P2093
Nakayama K
Shishido N
P304
P3181
P356
10.1016/S0092-8674(00)81237-4
P407
P577
1996-05-31T00:00:00Z