Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. - Wikidata - wikimedia - TriplyDB

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

http://www.wikidata.org/entity/Q29616540

about

Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors Transforming growth factor beta -inducible independent binding of SMAD to the Smad7 promoter Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway.Early endosomal regulation of Smad-dependent signaling in endothelial cells Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3 TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs Functional proteomics mapping of a human signaling pathway Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4 Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling Regulation of Hex gene expression by a Smads-dependent signaling pathway Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression SMAD6 contributes to patient survival in non-small cell lung cancer and its knockdown reestablishes TGF-beta homeostasis in lung cancer cells SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1 C18 ORF1, a novel negative regulator of transforming growth factor-β signaling Regulation of TG-interacting factor by transforming growth factor-beta Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.Bone morphogenetic protein-4-induced activation of Xretpos is mediated by Smads and Olf-1/EBF associated zinc finger (OAZ).Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1 Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development MUSI: an integrated system for identifying multiple specificity from very large peptide or nucleic acid data sets

P2860

Q22010204-955AA96D-785A-4DC6-AA58-3E5285326C0A Q22253348-33FE467A-799D-4C38-80B9-D16736472E76 Q22254141-5851C0BF-BE4C-42AD-A22D-BAB981ED7E91 Q24290996-D3E1593F-81F6-43F7-B2BC-3F0767DB028B Q24291279-F1C7CEB4-3570-419C-87DB-5ECDFD2062FB Q24292399-C442E6BF-64EA-4842-9DDA-85FC98E124F4 Q24294220-FCF8A785-4AC8-4206-BC48-AFF49F6C5C42 Q24294495-2E083C21-2346-4737-879A-900F30EBE4E1 Q24295158-D23207FA-742C-4122-881B-131BFE94BC58 Q24297719-AA7485D7-79F0-46A6-8AC7-ED7257FA607C Q24298398-555EF499-3DA8-483F-BFE2-E946A7DEB56E Q24299610-BBB21CF9-EB5C-4DEA-864C-C6AC0D4470CB Q24302554-8B823B56-10F0-4241-A193-F29AA00741FF Q24303530-6D656BD9-5C38-4651-8EFB-18FC898DE1A2 Q24304414-D3B9F471-E0DE-4600-814A-5B5073645498 Q24306193-16ED9963-BE6F-4D47-A54D-2BDA5837F1B8 Q24307591-EBFA0AA8-80DC-42DA-8ED4-6EB1EFB6F269 Q24310450-4C39FEDC-EC8D-4DE3-B227-0D615304B7C6 Q24313316-417C4829-664A-4FDB-AC24-43BF597F35D2 Q24315838-3F778CF3-2EEC-40D6-B1DD-2E8D525568BE Q24316099-1DC2676F-6D9A-4040-A9A4-7EC787AA128E Q24319956-203BFBE9-2052-435A-B803-661B4C9BF486 Q24320328-08C60CA4-3799-49D4-85EB-1BE604EA2EE2 Q24321923-DA2B5327-219F-402C-B7FD-22E2A01D58A7 Q24323374-2242813C-D273-43BB-9393-075ED2611B70 Q24336739-A3004780-7568-4800-B130-20D323AC796A Q24339143-AA95CFBD-FEC4-48A6-B44F-698C1FAEAF7A Q24529895-3C501CC8-84CD-4039-86A0-43EDA9A072B9 Q24534996-F91B2311-D0AE-49C8-983C-00EB66169164 Q24538036-F9CB05A2-FD14-4CD5-9836-06CCB9C200B2 Q24540349-2FA49C3B-AE60-44B0-B94B-E768E880A149 Q24548327-D94DC2CF-7B7C-44BF-8E26-B373CE7AB339 Q24554242-5E923CC5-E468-43CD-9D76-B4944340EB1A Q24562501-4A29A1A3-0A82-4DBF-8F3F-9ADD9C2374AE Q24563226-3B004BC9-7938-442B-8E11-02F08B5BCF1D Q24595443-04799052-AA79-4428-B32F-2A0F2CE4D454 Q24596458-4EB65E97-4BCC-458D-A8FD-37C6CD43BD8C Q24599753-C85D15B5-4F40-46FB-A6E8-0465611F4D63 Q24600802-E0F7D16D-4F91-497B-A503-1765584BBE17 Q24607812-3F1A8E05-6D6E-40F0-8203-7CDDB8BBB322

P2860

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

http://www.wikidata.org/entity/Q29616540

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@ast

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@en

type

label

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@ast

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@en

prefLabel

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@ast

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@en

P1433

Q29616540-B81AAF5D-0145-41C6-866F-A79B333E6F04

P1476

Q29616540-35034F8A-4BE6-4E34-92E8-A99F1709EDFB

P2093

Q29616540-3B7856FF-8B4B-48A9-87A1-A8F0AB1839C4

Q29616540-71A3908D-9EAD-4E8F-90BA-59426F81FF9F

Q29616540-742E1B7B-9AA6-4E2B-B4CB-138E9891318B

Q29616540-76618F7B-4D20-4537-BD30-31B34589977F

Q29616540-9DE74BE9-0EB4-4B1F-AB58-04F6E745FAC9

Q29616540-D4DD0AFE-8043-4D4B-A6B5-44E142ECE3C2

P2860

Q29616540-035B9FD2-E909-4353-9D0B-782B657B0CBC

Q29616540-05EBEC67-420E-432B-85CE-2B7D821282D0

Q29616540-0A190691-8359-4ABF-A60E-4AC5C0806559

Q29616540-108462D0-6C85-4F41-AA95-7AD1FACD1130

Q29616540-11148879-4785-43D5-AC51-B4C4128C5632

Q29616540-18FDFA36-5990-4151-BB0E-92883D65E3CF

Q29616540-1A6FDCBF-A65C-471B-A31B-CA2CB9043351

Q29616540-1BEF2726-E13F-4C74-AF36-4032A7ED0485

Q29616540-1D03155B-B2B8-40D1-86EB-9D778AD37765

Q29616540-1FA1ABFA-65F5-41D4-85E0-D4FC9460B96D

P304

Q29616540-22E0F614-DDC2-488A-8505-2D61CD464A6F

P31

Q29616540-5B03EB38-4B91-4354-BC5F-D113F2A23F6D

P3181

Q29616540-E9C119A9-D85C-4A48-8F4F-7309C7090DCC

P356

Q29616540-5F30B290-C3C4-433A-84B7-B757E4976E9A

P407

Q29616540-7D1BCAC5-BE85-4BEF-AF13-357366E63CFA

P433

Q29616540-404978DD-E534-4AA8-A399-6FB1C24BBFB5

P478

Q29616540-F7C56EDA-4B2A-4CC6-A265-DF66DDC1396F

P577

Q29616540-4D444ACB-2D7D-4F35-8E30-C6AD8F7C310B

P5875

Q29616540-E52BF37D-8694-42A1-949E-31E748116FEB

P698

Q29616540-1A697EF0-8E79-4AAE-BD13-A6948D931467

P932

Q29616540-1A8FD27E-AE64-418A-9468-9FD0AC51B567

P3181

P356

P1433

The EMBO Journal

P1476

Direct binding of Smad3 and Sm ...... tivator inhibitor-type 1 gene.

@en

P2093

Dennler S

http://www.w3.org/2001/XMLSchema#string

Gauthier JM

http://www.w3.org/2001/XMLSchema#string

Huet S

http://www.w3.org/2001/XMLSchema#string

Itoh S

http://www.w3.org/2001/XMLSchema#string

Vivien D

http://www.w3.org/2001/XMLSchema#string

ten Dijke P

http://www.w3.org/2001/XMLSchema#string

P2860

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

MADR1, a MAD-related protein that functions in BMP2 signaling pathways

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

TGF beta signals through a heteromeric protein kinase receptor complex

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.

A structural basis for mutational inactivation of the tumour suppressor Smad4

P304

3091-3100

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

274445

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/EMBOJ/17.11.3091

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P577

1998-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

13678413

http://www.w3.org/2001/XMLSchema#string

P698

9606191

http://www.w3.org/2001/XMLSchema#string

P932

1170648

http://www.w3.org/2001/XMLSchema#string