MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
about
Continued colonization of the human genome by mitochondrial DNASmad proteins function as co-modulators for MEF2 transcriptional regulatory proteinsDual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexesJab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradationTGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad415-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancersSmad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressorVascular MADs: two novel MAD-related genes selectively inducible by flow in human vascular endotheliumTranscriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivatorIdentification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1Molecular origins of cancer: Molecular basis of colorectal cancerTransforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding elementActivins and activin antagonists in hepatocellular carcinomaTransforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cellsTransforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer.Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarraysInduction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitroTumor evolution and intratumor heterogeneity in colorectal carcinoma: insights from comparative genomic profiling of primary tumors and matched metastasesMolecular alterations and biomarkers in colorectal cancerTargeting TGF-β signaling in cancerTargeting the Transforming Growth Factor-β Signaling in Cancer TherapyTGF-β - an excellent servant but a bad masterSMAD4 is a predictive marker for 5-fluorouracil-based chemotherapy in patients with colorectal cancer.Dysregulation of TGFβ1 Activity in Cancer and Its Influence on the Quality of Anti-Tumor ImmunityRole of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisDifferential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cellsThe TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancerGenomic structure and chromosomal localization of human thioredoxin-like protein gene (txl)Limiting the location of putative human prostate cancer tumor suppressor genes on chromosome 18qPathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Bone morphogenetic protein (BMP)-2 induces apoptosis in human myeloma cellsCharacterization of functional domains within Smad4/DPC4Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancerBRAM1, a BMP receptor-associated molecule involved in BMP signallingThe Discovery and Early Days of TGF-β: A Historical PerspectivePhysical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptorsSpecific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2Transforming growth factor beta1 induces nuclear export of inhibitory Smad7Altered expression and deletion of RMO1 in osteosarcoma
P2860
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P2860
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
description
1996 nî lūn-bûn
@nan
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@ast
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en-gb
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@nl
type
label
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@ast
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en-gb
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@nl
prefLabel
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@ast
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en-gb
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@nl
P2093
P50
P921
P3181
P1433
P1476
MADR2 maps to 18q21 and encode ...... utated in colorectal carcinoma
@en
P2093
G H Thomsen
L Attisano
S Gallinger
S W Scherer
P304
P3181
P356
10.1016/S0092-8674(00)80128-2
P407
P577
1996-08-23T00:00:00Z