Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
about
Diverse metastable structures formed by small oligomers of α-synuclein probed by force spectroscopyStructures of the E46K mutant-type α-synuclein protein and impact of E46K mutation on the structures of the wild-type α-synuclein proteinGenetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateRelationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicityCoordination features and affinity of the Cu²+ site in the α-synuclein protein of Parkinson's diseaseSynphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synucleinDequalinium-induced protofibril formation of alpha-synucleinAlpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recyclingMolecular determinants of α-synuclein mutants' oligomerization and membrane interactionsThe N-terminus of α-synuclein is essential for both monomeric and oligomeric interactions with membranesInteractions between fatty acids and alpha-synucleinMitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synucleinStructure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinementα-Synuclein occurs physiologically as a helically folded tetramer that resists aggregationSite-specific interaction between α-synuclein and membranes probed by NMR-observed methionine oxidation ratesStructures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopyMembrane curvature induction and tubulation are common features of synucleins and apolipoproteins.Secondary structure and dynamics of micelle bound beta- and gamma-synucleinIntrabody and Parkinson's diseaseResidual structure, backbone dynamics, and interactions within the synuclein familyα-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formationProperties of native brain α-synucleinNative α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2Versatile Structures of α-SynucleinFocus on Extracellular Vesicles: Exosomes and Their Role in Protein Trafficking and Biomarker Potential in Alzheimer's and Parkinson's DiseaseDynamic structural flexibility of α-synucleinTargeting heat shock proteins to modulate α-synuclein toxicityNovel subcellular localization for α-synuclein: possible functional consequencesBiophysical characterization of α-synuclein and its controversial structureExploring the accessible conformations of N-terminal acetylated α-synucleinA flash in the pan: dissecting dynamic amyloid intermediates using fluorescenceAlpha-synuclein biology in Lewy body diseasesFunction and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescencePropagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosisStructural Basis of Molecular Recognition of the Leishmania Small Hydrophilic Endoplasmic Reticulum-associated Protein (SHERP) at Membrane SurfacesNMR Structure of Calmodulin Complexed to an N-Terminally Acetylated α-Synuclein PeptideThe Synaptic Function of α-SynucleinThe contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's diseaseAnimal modeling an oligodendrogliopathy--multiple system atrophy
P2860
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P2860
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@ast
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@en
type
label
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@ast
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@en
prefLabel
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@ast
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@en
P50
P3181
P356
P1476
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes
@en
P2093
P304
P3181
P356
10.1074/JBC.273.16.9443
P407
P577
1998-04-01T00:00:00Z