Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication - Wikidata - wikimedia - TriplyDB

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

http://www.wikidata.org/entity/Q29617915

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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cells Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence Main roads to melanoma Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization How cells switch HIPK2 on and off Proapoptotic function of the retinoblastoma tumor suppressor protein Autophagy mediates the mitotic senescence transition F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1 Requirement of Cdk4 for v-Ha-ras-Induced Breast Tumorigenesis and Activation of the v-ras-Induced Senescence Program by the R24C Mutation Targeting ATR and Chk1 kinases for cancer treatment: a new model for new (and old) drugs Alternative cyclin D1 splice forms differentially regulate the DNA damage response Unbalanced replication as a major source of genetic instability in cancer cells Senescence of activated stellate cells limits liver fibrosis Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence Prevention of DNA re-replication in eukaryotic cells Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging Replication licensing and cancer--a fatal entanglement?E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2 p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms Mechanisms to control rereplication and implications for cancer.Two faces of p53: aging and tumor suppression Extracellular Vesicles as New Players in Cellular Senescence Multiple facets of p53 in senescence induction and maintenance Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy Connecting the Dots: From DNA Damage and Repair to Aging Cellular Senescence as the Causal Nexus of Aging Cellular senescence in aging and age-related disease: from mechanisms to therapy Linking replication stress with heterochromatin formation Replication Stress: A Lifetime of Epigenetic Change Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy The impact of cellular senescence in cancer therapy: is it true or not?Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability Molecular pathways: targeting the dependence of mutant RAS cancers on the DNA damage response Disruptive chemicals, senescence and immortality Therapeutic targeting of replicative immortality Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

http://www.wikidata.org/entity/Q29617915

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

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2006年论文

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name

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

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Aaron Bensimon

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Angelo Cicalese

http://www.w3.org/2001/XMLSchema#string

Catherine Schurra

http://www.w3.org/2001/XMLSchema#string

Chiara Luise

http://www.w3.org/2001/XMLSchema#string

Massimiliano Garre'

http://www.w3.org/2001/XMLSchema#string

Pier Giuseppe Pelicci

http://www.w3.org/2001/XMLSchema#string

Sara Piccinin

http://www.w3.org/2001/XMLSchema#string

P2860

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Loss of Geminin induces rereplication in the presence of functional p53

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Cell-cycle checkpoints and cancer

ATR Regulates Fragile Site Stability

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

A DNA damage checkpoint response in telomere-initiated senescence

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638-642

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scholarly article

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252836

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10.1038/NATURE05327

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P433

7119

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444

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Patrizia Gasparini

F d'Adda di Fagagna

Raffaella Di Micco

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2006-11-01T00:00:00Z

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6662847

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1007876716

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17136094

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