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Master transcription factors and mediator establish super-enhancers at key cell identity genes

Master transcription factors and mediator establish super-enhancers at key cell identity genes

http://www.wikidata.org/entity/Q29618062

about

The basal transcription machinery as a target for cancer therapy JARID1B is a luminal lineage-driving oncogene in breast cancer Enhancer activation requires trans-recruitment of a mega transcription factor complex Stress-triggered atavistic reprogramming (STAR) addiction: driving force behind head and neck cancer?The Chromatin Signature of Pluripotency: Establishment and Maintenance DNA Methylation in Skeletal Muscle Stem Cell Specification, Proliferation, and Differentiation.Effects of the lifestyle habits in breast cancer transcriptional regulation Mutations, kataegis and translocations in B cells: understanding AID promiscuous activity Regulation of MYC gene expression by aberrant Wnt/β-catenin signaling in colorectal cancer Common stemness regulators of embryonic and cancer stem cells Decoding the non-coding genome: elucidating genetic risk outside the coding genome The search for cis-regulatory driver mutations in cancer genomes Transcriptional enhancers: functional insights and role in human disease Architectural and Functional Commonalities between Enhancers and Promoters Chromatin organization in pluripotent cells: emerging approaches to study and disrupt function Mediator kinase module and human tumorigenesis Exploiting genomics and natural genetic variation to decode macrophage enhancers SMC complexes link gene expression and genome architecture The Mediator complex: a central integrator of transcription Dynamics of histone variant H3.3 and its coregulation with H2A.Z at enhancers and promoters Chromatin features and the epigenetic regulation of pluripotency states in ESCs Super-enhancers: Asset management in immune cell genomes Enhancer malfunction in cancer DNA topology and transcription Investigating the transcriptional control of cardiovascular development From trans to cis: transcriptional regulatory networks in neocortical development Chromatin dynamics during cellular reprogramming Mechanisms Underlying the Selection and Function of Macrophage-Specific Enhancers Getting up to speed with transcription elongation by RNA polymerase II Homotypic clusters of transcription factor binding sites: A model system for understanding the physical mechanics of gene expression Social exclusion changes histone modifications H3K4me3 and H3K27ac in liver tissue of wild house mice Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis.Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion BET inhibitors in the treatment of hematologic malignancies: current insights and future prospects Emerging concepts of epigenetic dysregulation in hematological malignancies Deciphering the Epigenetic Code in Embryonic and Dental Pulp Stem Cells H2A.Z: a molecular rheostat for transcriptional control The selection and function of cell type-specific enhancers Towards an understanding of kidney diseases associated with WT1 mutations The mechanisms behind the therapeutic activity of BET bromodomain inhibition

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Master transcription factors and mediator establish super-enhancers at key cell identity genes

http://www.wikidata.org/entity/Q29618062

description

2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2013

@ast

im April 2013 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: 11 April 2013)

@en

wetenschappelijk artikel (gepubliceerd op 2013/04/11)

@nl

наукова стаття, опублікована у квітні 2013

@uk

مقالة علمية (نشرت في 11-4-2013)

@ar

name

Master transcription factors a ...... ers at key cell identity genes

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Master transcription factors a ...... ers at key cell identity genes

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type

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Master transcription factors a ...... ers at key cell identity genes

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Master transcription factors a ...... ers at key cell identity genes

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Abraham BJ

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Hnisz D

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Kagey MH

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Lin CY

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Orlando DA

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Rahl PB

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Whyte WA

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Young RA

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Model-based analysis of ChIP-Seq (MACS)

Classification of human genomic regions based on experimentally determined binding sites of more than 100 transcription-related factors

Transcriptional Regulatory Elements in the Human Genome

An integrated encyclopedia of DNA elements in the human genome

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

Core transcriptional regulatory circuitry in human embryonic stem cells

The accessible chromatin landscape of the human genome

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Mediator and cohesin connect gene expression and chromatin architecture

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