Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
about
The roles of ASK family proteins in stress responses and diseasesThe interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.RIP3, a novel apoptosis-inducing kinasec-E10 is a caspase-recruiting domain-containing protein that interacts with components of death receptors signaling pathway and activates nuclear factor-kappaBTRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis inductionCleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosisFunctional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirementsMIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule networkStat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activationThe apoptotic signaling pathway activated by Toll-like receptor-2T6BP, a TRAF6-interacting protein involved in IL-1 signalingInterchangeable binding of Bcl10 to TRAF2 and cIAPs regulates apoptosis signalingInvolvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneKeratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADDThe tyrosine kinase Syk regulates TPL2 activation signalsDe-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signallingAIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activationUXT is a novel and essential cofactor in the NF-kappaB transcriptional enhanceosomeHuman glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signalsTAK1-dependent signaling requires functional interaction with TAB2/TAB3Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell deathEpstein-Barr virus-encoded latent membrane protein 1 activates the JNK pathway through its extreme C terminus via a mechanism involving TRADD and TRAF2Molecular determinants of NF-kappaB-inducing kinase actionTNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitinationTAB3, a new binding partner of the protein kinase TAK1c-Jun regulates cell cycle progression and apoptosis by distinct mechanismsImpaired neural tube closure, axial skeleton malformations, and tracheal ring disruption in TRAF4-deficient mice.Stress-induced decrease in TRAF2 stability is mediated by Siah2The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNFRestoration of NF-kappaB activation by tumor necrosis factor alpha receptor complex-targeted MEKK3 in receptor-interacting protein-deficient cellsRANK is essential for osteoclast and lymph node developmentMKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokinesSignaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domainDeficiency of T2K leads to apoptotic liver degeneration and impaired NF-kappaB-dependent gene transcriptionThe atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathwayRole of the TAB2-related protein TAB3 in IL-1 and TNF signalingCD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligandTRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaBPKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitinationTumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
P2860
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P2860
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Early lethality, functional NF ...... death in TRAF2-deficient mice
@ast
Early lethality, functional NF ...... death in TRAF2-deficient mice
@en
type
label
Early lethality, functional NF ...... death in TRAF2-deficient mice
@ast
Early lethality, functional NF ...... death in TRAF2-deficient mice
@en
prefLabel
Early lethality, functional NF ...... death in TRAF2-deficient mice
@ast
Early lethality, functional NF ...... death in TRAF2-deficient mice
@en
P2093
P3181
P1433
P1476
Early lethality, functional NF ...... death in TRAF2-deficient mice
@en
P2093
Goeddel DV
Shahinian A
P304
P3181
P356
10.1016/S1074-7613(00)80391-X
P407
P577
1997-11-01T00:00:00Z