Regulation of aging and age-related disease by DAF-16 and heat-shock factor
about
Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegansRole of CBP and SATB-1 in aging, dietary restriction, and insulin-like signalingMalate and fumarate extend lifespan in Caenorhabditis elegansIdentification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegansPhosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 bindingSilent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activityA novel HSF1-mediated death pathway that is suppressed by heat shock proteinsAge-related changes of nuclear architecture in Caenorhabditis elegansLessons from C. elegans: signaling pathways for longevitySpatial protein quality control and the evolution of lineage-specific ageingAging as an event of proteostasis collapseExtreme-longevity mutations orchestrate silencing of multiple signaling pathwaysCollapse of proteostasis represents an early molecular event in Caenorhabditis elegans agingFOXO3A genotype is strongly associated with human longevityHeat shock factor 1 is a powerful multifaceted modifier of carcinogenesisAnalysis of phosphorylation of human heat shock factor 1 in cells experiencing a stressNew genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen.Uncoupling of longevity and telomere length in C. elegans.Olive Oil and the Hallmarks of AgingLong live FOXO: unraveling the role of FOXO proteins in aging and longevityThe wonderous chaperones: A highlight on therapeutics of cancer and potentially malignant disordersRegulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genesPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Proteostasis and longevity: when does aging really begin?FOXO transcription factors: key regulators of cellular quality controlLongitudinal measures of proteostasis in live neurons: features that determine fate in models of neurodegenerative diseaseMitochondrial proteostasis in the control of aging and longevityGenetics, life span, health span, and the aging process in Caenorhabditis elegansChemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosisRegulation of cellular protein quality control networks in a multicellular organismThe regulation of the autophagic network and its implications for human diseaseHsp70 May Be a Molecular Regulator of Schistosome Host InvasionImmunolocalization of anti-hsf1 to the acetabular glands of infectious schistosomes suggests a non-transcriptional function for this transcriptional activatorC. elegans VANG-1 modulates life span via insulin/IGF-1-like signalingAngiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life SpanDAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegansGermline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegansGlobal functional analyses of cellular responses to pore-forming toxinsThe Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signalsDAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans
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Regulation of aging and age-related disease by DAF-16 and heat-shock factor
description
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2003
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im Mai 2003 veröffentlichter wissenschaftlicher Artikel
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scientific article (publication date: 16 May 2003)
@en
wetenschappelijk artikel (gepubliceerd op 2003/05/16)
@nl
наукова стаття, опублікована в травні 2003
@uk
مقالة علمية (نشرت في 16-5-2003)
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name
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
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Regulation of aging and age-related disease by DAF-16 and heat-shock factor
@en
type
label
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
@ast
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
@en
prefLabel
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
@ast
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
@en
P2093
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P1476
Regulation of aging and age-related disease by DAF-16 and heat-shock factor
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P2093
P304
P3181
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10.1126/SCIENCE.1083701
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P577
2003-05-16T00:00:00Z