Phosphatidylinositol-3-OH kinase as a direct target of Ras
about
PI3K/AKT/mTOR Pathway in AngiogenesisMulti-determinants analysis of molecular alterations for predicting clinical benefit to EGFR-targeted monoclonal antibodies in colorectal cancerPremature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingHuman phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activityA phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsRole of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cellsRegulation of brain-derived neurotrophic factor exon IV transcription through calcium responsive elements in cortical neuronsSecond AKT: the rise of SGK in cancer signallingNaturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitorsAkt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factorP110delta, a novel phosphoinositide 3-kinase in leukocytesRaf family kinases: old dogs have learned new tricksRas activation in platelets after stimulation of the thrombin receptor, thromboxane A2 receptor or protein kinase CProtein binding and signaling properties of RIN1 suggest a unique effector functionA human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting systemRegulation of growth and survival of activated T cells by cell-transducing inhibitors of RasIdentification of a novel guanine nucleotide exchange factor for the Rho GTPaseThe RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3ets-2 is a target for an akt (Protein kinase B)/jun N-terminal kinase signaling pathway in macrophages of motheaten-viable mutant miceMultiple ras downstream pathways mediate functional repression of the homeobox gene product TTF-1IRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisThe heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytesActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationInhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cellsThe leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and RafRetroviral oncogenes: a historical primerThe Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationTargeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria.Interaction of activated Ras with Raf-1 alone may be sufficient for transformation of rat2 cellsTumours with PI3K activation are resistant to dietary restrictionA human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1Activation of CD4 T cells by Raf-independent effectors of RasAstrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegenerationAn essential role for RasGRP1 in mast cell function and IgE-mediated allergic responseRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationThe Ras target AF-6 is a substrate of the fam deubiquitinating enzymeLeptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K dependent actin reorganization and KATP channel activationNovel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cellsPIKE GTPase signaling and function
P2860
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P2860
Phosphatidylinositol-3-OH kinase as a direct target of Ras
description
1994 nî lūn-bûn
@nan
1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@ast
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@en
type
label
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@ast
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@en
prefLabel
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@ast
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@en
P2093
P3181
P356
P1433
P1476
Phosphatidylinositol-3-OH kinase as a direct target of Ras
@en
P2093
Rodriguez-Viciana P
Vanhaesebroeck B
Waterfield MD
P2888
P304
P3181
P356
10.1038/370527A0
P407
P577
1994-08-01T00:00:00Z
P5875
P6179
1052561899