Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
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A gain-of-function mutation in STAT6The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6The zinc finger protein Gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3Interferon-kappa, a novel type I interferon expressed in human keratinocytesPIKE-A is required for prolactin-mediated STAT5a activation in mammary gland developmentRespiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoterRequirements for interleukin-4-induced gene expression and functional characterization of Stat6Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptorMutational analysis of the STAT6 SH2 domainInteraction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domainsJAK/STAT but not ERK1/ERK2 pathway mediates interleukin (IL)-6/soluble IL-6R down-regulation of Type II collagen, aggrecan core, and link protein transcription in articular chondrocytes. Association with a down-regulation of SOX9 expressionIRT-1, a novel interferon-gamma-responsive transcript encoding a growth-suppressing basic leucine zipper proteinInteraction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signalingPhosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 proteinThe SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signalsInterferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation14-3-3zeta interacts with the alpha-chain of human interleukin 9 receptorPhysical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathwaysSer727-dependent recruitment of MCM5 by Stat1alpha in IFN-gamma-induced transcriptional activation.Protein kinase PKR is required for platelet-derived growth factor signaling of c-fos gene expression via Erks and Stat3.Antiviral actions of interferonsGRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interactionThe Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factorsTranscriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switchingCucurbitacins - a promising target for cancer therapyGenomic views of STAT function in CD4+ T helper cell differentiationIdentification of two residues in MCM5 critical for the assembly of MCM complexes and Stat1-mediated transcription activation in response to IFN-gammaCutting edge: selective tyrosine dephosphorylation of interferon-activated nuclear STAT5 by the VHR phosphataseFunctional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signalingInteractions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complexTwo contact regions between Stat1 and CBP/p300 in interferon gamma signalingLineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4Dysregulated T cell expression of TIM3 in multiple sclerosisJak1 kinase is required for cell migrations and anterior specification in zebrafish embryosTargeted disruption of the mouse Stat3 gene leads to early embryonic lethalityImpaired development of CD4+ CD25+ regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease.A Central Role for STAT3 in Gammaherpesvirus-Life Cycle and -DiseasesTargeted Therapies in Liver Fibrosis: Combining the Best Parts of Platelet-Derived Growth Factor BB and Interferon GammaSignal Transducers and Activators of Transcription (STAT) Regulatory Networks in Marine Organisms: From Physiological Observations towards Marine Drug Discovery
P2860
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P2860
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
description
1995 nî lūn-bûn
@nan
1995 թուականին հրատարակուած գիտական յօդուած
@hyw
1995 թվականին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@ast
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@en
type
label
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@ast
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@en
prefLabel
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@ast
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@en
P3181
P1476
Transcriptional responses to polypeptide ligands: the JAK-STAT pathway
@en
P2093
Darnell JE Jr
Schindler C
P304
P3181
P356
10.1146/ANNUREV.BI.64.070195.003201
P407
P577
1995-01-01T00:00:00Z