Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality - Wikidata - wikimedia - TriplyDB

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

http://www.wikidata.org/entity/Q24685515

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Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6 The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways Crif1 is a novel transcriptional coactivator of STAT3 STAT1 activation regulates proliferation and differentiation of renal progenitors Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3 Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells gp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathways Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development.Linear and cooperative signaling: roles for Stat proteins in the regulation of cell survival and apoptosis in the mammary epithelium.Signaling by STATs Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma A Central Role for STAT3 in Gammaherpesvirus-Life Cycle and -Diseases Skeletal muscle wasting and renewal: a pivotal role of myokine IL-6 Mitochondrial Stat3, the Need for Design Thinking Cancer Stem Cell Hierarchy in Glioblastoma Multiforme Signal transducer and activator of transcription 3 regulation by novel binding partners STATs: An Old Story, Yet Mesmerizing The Complex Role of STAT3 in Viral Infections LIF-STAT signaling and trophoblast biology STAT3 and the Hyper-IgE syndrome: Clinical presentation, genetic origin, pathogenesis, novel findings and remaining uncertainties Hyper-IgE syndrome update STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy Functions of the Drosophila JAK-STAT pathway: Lessons from stem cells An update on the hyper-IgE syndromes IL-6-mediated activation of Stat3α prevents trauma/hemorrhagic shock-induced liver inflammation The role of STAT3 in autophagy FER kinase activation of Stat3 is determined by the N-terminal sequence Tip60 is a co-repressor for STAT3 Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a Specific inhibition of Stat3 signal transduction by PIAS3 Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer Clinical manifestations, etiology, and pathogenesis of the hyper-IgE syndromes The LIM/homeodomain protein Islet1 recruits Janus tyrosine kinases and signal transducer and activator of transcription 3 and stimulates their activities A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation Physical and functional interactions between STAT3 and ZIP kinase

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

http://www.wikidata.org/entity/Q24685515

description

1997 nî lūn-bûn

@nan

1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

1997年の論文

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1997年論文

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1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@ast

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@en

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@nl

type

label

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@ast

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@en

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@nl

prefLabel

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@ast

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@en

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

@en

P2093

K Noguchi

http://www.w3.org/2001/XMLSchema#string

K Takeda

http://www.w3.org/2001/XMLSchema#string

M Matsumoto

http://www.w3.org/2001/XMLSchema#string

N Yoshida

http://www.w3.org/2001/XMLSchema#string

S Akira

http://www.w3.org/2001/XMLSchema#string

T Kishimoto

http://www.w3.org/2001/XMLSchema#string

T Tanaka

http://www.w3.org/2001/XMLSchema#string

W Shi

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

Essential role of Stat6 in IL-4 signalling

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

Implantation and the placenta: key pieces of the development puzzle.

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