about
Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4EmTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4ESumoylation of eIF4E activates mRNA translationPostnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmissionTranslational homeostasis via the mRNA cap-binding protein, eIF4EDistinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.Regulation of mTOR and cell growth in response to energy stress by REDD1.Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2)Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signalingElucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinaseRegulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.Dengue virus utilizes a novel strategy for translation initiation when cap-dependent translation is inhibited8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathwaysThe C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylationRegulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complexMammalian target of rapamycin: a central node of complex signaling cascadesS6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathwaymTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityDelta-tocotrienol protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signalingReduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expressionRegulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylationRheb and mTOR regulate neuronal polarity through Rap1BTargeting the mTOR signaling network for cancer therapyHuman cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexesA MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signallingSplice variants and expression patterns of SHEP1, BCAR3 and NSP1, a gene family involved in integrin and receptor tyrosine kinase signalingPten dose dictates cancer progression in the prostateTranslation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1Overcoming cisplatin resistance by mTOR inhibitor in lung cancer.Human Cytomegalovirus Strategies to Maintain and Promote mRNA TranslationRegulation of global and specific mRNA translation by the mTOR signaling pathwayDysregulation and restoration of translational homeostasis in fragile X syndromeHomeostatic plasticity at the Drosophila neuromuscular junctionThe role and regulation of mTOR in T-lymphocyte function'Ribozoomin'--translation initiation from the perspective of the ribosome-bound eukaryotic initiation factors (eIFs)mTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsMultimodal management of muscle-invasive bladder cancerO-GlcNAcylation and Metabolic Reprograming in CancerFlavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus Infection
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Regulation of translation initiation by FRAP/mTOR
@ast
Regulation of translation initiation by FRAP/mTOR
@en
type
label
Regulation of translation initiation by FRAP/mTOR
@ast
Regulation of translation initiation by FRAP/mTOR
@en
prefLabel
Regulation of translation initiation by FRAP/mTOR
@ast
Regulation of translation initiation by FRAP/mTOR
@en
P3181
P356
P1433
P1476
Regulation of translation initiation by FRAP/mTOR
@en
P2093
P304
P3181
P356
10.1101/GAD.887201
P407
P577
2001-04-01T00:00:00Z