Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway
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Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to orangesc-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer's DiseaseAmyloid-β Receptors: The Good, the Bad, and the Prion ProteinBlood-Based Proteomic Biomarkers of Alzheimer's Disease PathologyWnts in action: from synapse formation to synaptic maintenanceIs L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type miceAlzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and GammaDysfunction of Wnt signaling and synaptic disassembly in neurodegenerative diseases.The role of Wnt signaling in the development of Alzheimer's disease: a potential therapeutic target?Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's diseaseTIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone.NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology.Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's diseaseThe role of clusterin in amyloid-β-associated neurodegeneration.Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing.Influence of Sex on Basal and Dickkopf-1 Regulated Gene Expression in the Bovine Morula.A correlativity study of plasma APL1β28 and clusterin levels with MMSE/MoCA/CASI in aMCI patients.Rationalising the role of Keratin 9 as a biomarker for Alzheimer's disease.Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of agingThe importance of tau phosphorylation for neurodegenerative diseasesAge-dependent effect of Alzheimer's risk variant of CLU on EEG alpha rhythm in non-demented adults.The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model.An unexpected role for a Wnt-inhibitor: Dickkopf-1 triggers a novel cancer survival mechanism through modulation of aldehyde-dehydrogenase-1 activity.WNT signaling in neuronal maturation and synaptogenesis.Wnts in adult brain: from synaptic plasticity to cognitive deficiencies.Clusterin in Alzheimer's disease: a player in the biological behavior of amyloid-betaWnt signaling in the nervous system and in Alzheimer's disease.Signaling pathway cross talk in Alzheimer's diseaseThe chaperone protein clusterin may serve as a cerebrospinal fluid biomarker for chronic spinal cord disorders in the dog.Early growth response-1-mediated down-regulation of drebrin correlates with loss of dendritic spines.Cognitive decline in Parkinson disease.Rationale for targeting the Wnt signalling modulator Dickkopf-1 for oncology.Aberrant Wnt signaling: a special focus in CNS diseases.Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of β-Secretase 1 (BACE-1) in the BrainReversal of Synapse Degeneration by Restoring Wnt Signaling in the Adult Hippocampus.Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal NeuronsImpaired autophagy: a link between neurodegenerative and neuropsychiatric diseases.Derailed intraneuronal signalling drives pathogenesis in sporadic and familial Alzheimer's disease.Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis.Consequences of endogenous and exogenous WNT signaling for development of the preimplantation bovine embryo.
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P2860
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@ast
Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@en
type
label
Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@ast
Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@en
prefLabel
Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@ast
Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@en
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P2860
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P921
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Clusterin regulates β-amyloid ...... ion of the wnt-PCP-JNK pathway
@en
P2093
C Fernandes
C H Reynolds
J Stephenson
M Causevic
P2860
P2888
P3181
P356
10.1038/MP.2012.163
P407
P50
P577
2012-11-20T00:00:00Z
P5875
P6179
1009234054