Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
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The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivoOntogeny of apelin and its receptor in the rodent gastrointestinal tractThe Apelin-APJ System in the Evolution of Heart FailureAgonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptorsApelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathwayCellular localization of apelin and its receptor in the anterior pituitary: evidence for a direct stimulatory action of apelin on ACTH releaseApelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin releaseIn vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failureToddler: an embryonic signal that promotes cell movement via Apelin receptors.Transcriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptideRegulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders.Genetic variants in the apelin system and blood pressure responses to dietary sodium interventions: a family-based association study.Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanineRevolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10.Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling.Pressor effect of apelin-13 in the rostral ventrolateral medulla: role of NAD(P)H oxidase-derived superoxideNovel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets.Effect of volume expansion with hypertonic- and isotonic saline and isotonic glucose on sodium and water transport in the principal cells in the kidneyApelin-13 inhibits large-conductance Ca2+-activated K+ channels in cerebral artery smooth muscle cells via a PI3-kinase dependent mechanism.Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging.Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonistApelin-13 enhances arcuate POMC neuron activity via inhibiting M-currentApela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling.Central and peripheral apelin receptor distribution in the mouse: species differences with ratTreatment with metformin and a dipeptidyl peptidase-4 inhibitor elevates apelin levels in patients with type 2 diabetes mellitus.Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells--brief report.Stress-dependent and gender-specific neuroregulatory roles of the apelin receptor in the hypothalamic-pituitary-adrenal axis response to acute stress.Reciprocal regulation of plasma apelin and vasopressin by osmotic stimuliApelin inhibits diet-induced obesity by enhancing lymphatic and blood vessel integrity.The apelin receptor: physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR.Apelin is decreased with human preterm and term labor and regulates prolabor mediators in human primary amnion cellsIncreased bone mass in mice lacking the adipokine apelin.The effects of apelin on the electrical activity of hypothalamic magnocellular vasopressin and oxytocin neurons and somatodendritic Peptide release.The role of apelin in cardiovascular function and heart failure.Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats.Abnormal fluid homeostasis in apelin receptor knockout miceApelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats.Physiological regulation of magnocellular neurosecretory cell activity: integration of intrinsic, local and afferent mechanisms.Apelin is a positive regulator of ACE2 in failing hearts.
P2860
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P2860
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
description
2001 nî lūn-bûn
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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2001 թվականի մայիսին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年論文
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2001年论文
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name
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
@ast
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
@en
type
label
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
@ast
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
@en
prefLabel
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
@ast
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain.
@en
P2093
P50
P3181
P1476
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain
@en
P2093
P304
P3181
P356
10.1046/J.1471-4159.2001.00320.X
P407
P577
2001-05-01T00:00:00Z