Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells. - Wikidata - wikimedia - TriplyDB

Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.

Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.

http://www.wikidata.org/entity/Q30032296

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Immunohistochemical examination for the distribution of podoplanin-expressing cells in developing mouse molar tooth germs Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice The fungal pattern recognition receptor, Dectin-1, and the associated cluster of C-type lectin-like receptors Crystal structure of rhodocytin, a ligand for the platelet-activating receptor CLEC-2 Podoplanin associates with adverse postoperative prognosis of patients with clear cell renal cell carcinoma Podoplanin - a small glycoprotein with many faces Lymphangiogenesis and Lesion Heterogeneity in Interstitial Lung Diseases The role of platelets in the recruitment of leukocytes during vascular disease Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR New horizon in platelet function: with special reference to a recently-found molecule, CLEC-2 Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2 Renal cells activate the platelet receptor CLEC-2 through podoplanin Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2).Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2.Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin Recent advances in the pathobiology and management of Kasabach-Merritt phenomenon.Elevated Soluble Platelet Glycoprotein VI Levels in Patients After Living Donor Liver Transplantation.Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation.Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation Immunoelectron microscopic study of podoplanin localization in mouse salivary gland myoepithelium Mutation of threonine 34 in mouse podoplanin-Fc reduces CLEC-2 binding and toxicity in vivo while retaining antilymphangiogenic activity.A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin.The lymphatic system in health and disease.CLEC-2-dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP Platelets and cancer: a casual or causal relationship: revisited.Mucin-type O-glycosylation is critical for vascular integrity.Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis.Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets.Inhibitory C-type lectin receptors in myeloid cells.C-type lectin like receptor 2 (CLEC-2) signals independently of lipid raft microdomains in platelets.An overview of lymphatic vessels and their emerging role in cardiovascular disease Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.Human podoplanin-positive monocytes and platelets enhance lymphangiogenesis through the activation of the podoplanin/CLEC-2 axis Signaling by myeloid C-type lectin receptors in immunity and homeostasis Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis.

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Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.

http://www.wikidata.org/entity/Q30032296

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2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Involvement of the snake toxin ...... t activation, by cancer cells.

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Involvement of the snake toxin ...... t activation, by cancer cells.

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Involvement of the snake toxin ...... t activation, by cancer cells.

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Involvement of the snake toxin ...... t activation, by cancer cells.

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Involvement of the snake toxin ...... t activation, by cancer cells.

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Involvement of the snake toxin ...... t activation, by cancer cells.

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Journal of Biological Chemistry

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Involvement of the snake toxin ...... et activation, by cancer cells

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Katsue Suzuki-Inoue

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Kazuhiko Mishima

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Mika Kato Kaneko

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Osamu Inoue

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Yasuo Yamazaki

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Yukio Ozaki

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P2860

Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells

Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR

Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors

Platelet-collagen interaction: is GPVI the central receptor?

Analysis of the interaction of platelet collagen receptor glycoprotein VI (GPVI) with collagen. A dimeric form of GPVI, but not the monomeric form, shows affinity to fibrous collagen

Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors

Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling

Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma

Functional sialylated O-glycan to platelet aggregation on Aggrus (T1alpha/Podoplanin) molecules expressed in Chinese hamster ovary cells

Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression

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3147602

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10.1074/JBC.M702327200

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36

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282

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Hisashi Narimatsu

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2007-07-06T00:00:00Z

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17616532

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positive regulation of platelet aggregation