Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development
about
The calcium signaling toolkit of the Apicomplexan parasites Toxoplasma gondii and Plasmodium sppPhosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion.Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1Optimization of an imidazopyridazine series of inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1).PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum.The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival.Destabilization domain approach adapted for regulated protein expression in the protozoan parasite Entamoeba histolytica.Plasmodium berghei calcium dependent protein kinase 1 is not required for host cell invasion.The calcium-dependent protein kinase 3 of toxoplasma influences basal calcium levels and functions beyond egress as revealed by quantitative phosphoproteome analysisGenome-wide expression patterns of calcium-dependent protein kinases in Toxoplasma gondii.Allosteric activation of apicomplexan calcium-dependent protein kinases.Molecular Characterization and Functional Analysis of a Novel Calcium-Dependent Protein Kinase 4 from Eimeria tenellaAnalysis of Noncanonical Calcium-Dependent Protein Kinases in Toxoplasma gondii by Targeted Gene Deletion Using CRISPR/Cas9.Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analoguesReduced Activity of Mutant Calcium-Dependent Protein Kinase 1 Is Compensated in Plasmodium falciparum through the Action of Protein Kinase G.Expression of the essential Kinase PfCDPK1 from Plasmodium falciparum in Toxoplasma gondii facilitates the discovery of novel antimalarial drugsDesigning selective inhibitors for calcium-dependent protein kinases in apicomplexans.Calcium signalling in malaria parasites.Enzyme Activity Assays for Protein Kinases: Strategies to Identify Active Substrates.Signaling Strategies of Malaria Parasite for Its Survival, Proliferation, and Infection during Erythrocytic Stage.The serine/threonine phosphatases of apicomplexan parasites.Plasmodium falciparum Calcium-Dependent Protein Kinase 2 Is Critical for Male Gametocyte Exflagellation but Not Essential for Asexual Proliferation.PfCDPK1 is critical for malaria parasite gametogenesis and mosquito infection.A forward genetic screen identifies a negative regulator of rapid Ca2+-dependent cell egress (MS1) in the intracellular parasite Toxoplasma gondii.Assessment of phosphorylation in Toxoplasma glideosome assembly and function.Calcium-Dependent Protein Kinase 5 Is Required for Release of Egress-Specific Organelles in Plasmodium falciparum.Calcium-dependent phosphorylation of Plasmodium falciparum serine repeat antigen-5 triggers merozoite egress.
P2860
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P2860
Inhibition of Plasmodium falciparum CDPK1 by conditional expression of its J-domain demonstrates a key role in schizont development
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Inhibition of Plasmodium falci ...... y role in schizont development
@ast
Inhibition of Plasmodium falci ...... y role in schizont development
@en
type
label
Inhibition of Plasmodium falci ...... y role in schizont development
@ast
Inhibition of Plasmodium falci ...... y role in schizont development
@en
prefLabel
Inhibition of Plasmodium falci ...... y role in schizont development
@ast
Inhibition of Plasmodium falci ...... y role in schizont development
@en
P2093
P2860
P50
P921
P356
P1433
P1476
Inhibition of Plasmodium falci ...... y role in schizont development
@en
P2093
Brendan S Crabb
Catherine Q Nie
Efrosinia Krejany
Paul R Gilson
Paul R Sanders
P2860
P304
P356
10.1042/BJ20130124
P407
P577
2013-06-01T00:00:00Z