Conformational dynamics of single pre-mRNA molecules during in vitro splicing. - Wikidata - wikimedia - TriplyDB

Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

http://www.wikidata.org/entity/Q30053690

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Ultra-stable organic fluorophores for single-molecule research smFRET studies of the 'encounter' complexes and subsequent intermediate states that regulate the selectivity of ligand binding Single molecule fluorescence approaches shed light on intracellular RNAs New insights into the spliceosome by single molecule fluorescence microscopy Kinetic fingerprinting to identify and count single nucleic acids The Shine-Dalgarno sequence of riboswitch-regulated single mRNAs shows ligand-dependent accessibility bursts Cryo-EM structure of the spliceosome immediately after branching Conformational dynamics of stem II of the U2 snRNA.Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure Single-Molecule Pull-Down FRET to Dissect the Mechanisms of Biomolecular Machines Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.Single-molecule tools for enzymology, structural biology, systems biology and nanotechnology: an update.Mechanisms and Regulation of Alternative Pre-mRNA Splicing Proofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control.Evidence for a group II intron-like catalytic triplex in the spliceosome Coupling mRNA processing with transcription in time and space.Biological mechanisms, one molecule at a time Single-molecule approach to immunoprecipitated protein complexes: insights into miRNA uridylation.Pre-mRNA splicing during transcription in the mammalian system.Rapid isolation and single-molecule analysis of ribonucleoproteins from cell lysate by SNAP-SiMPull Functional roles of protein splicing factors.The spliceosome: a flexible, reversible macromolecular machine.Bringing single-molecule spectroscopy to macromolecular protein complexes.Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site.Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics Single molecule analysis reveals reversible and irreversible steps during spliceosome activation Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.What have single-molecule studies taught us about gene expression?A 10S galectin-3-U1 snRNP complex assembles into active spliceosomes.The spliceosome: disorder and dynamics defined.RNA biology in a test tube--an overview of in vitro systems/assays.Staying on message: ensuring fidelity in pre-mRNA splicing.Studying genomic processes at the single-molecule level: introducing the tools and applications.Probing nucleic acid interactions and pre-mRNA splicing by Förster Resonance Energy Transfer (FRET) microscopy A day in the life of the spliceosome Single-molecule fluorescence-based studies on the dynamics, assembly and catalytic mechanism of the spliceosome.Single-Molecule Analysis of Pre-mRNA Splicing with Colocalization Single-Molecule Spectroscopy (CoSMoS).Methodologies for studying the spliceosome's RNA dynamics with single-molecule FRET.Lights, camera, action! Capturing the spliceosome and pre-mRNA splicing with single-molecule fluorescence microscopy.Quantifying the Assembly of Multicomponent Molecular Machines by Single-Molecule Total Internal Reflection Fluorescence Microscopy

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P2860

Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

http://www.wikidata.org/entity/Q30053690

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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type

label

Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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Nature Structural & Molecular Biology

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Conformational dynamics of single pre-mRNA molecules during in vitro splicing.

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Christine Guthrie

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Corina Maeder

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Daniel E Ryan

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Franklin Fuller

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Jeffrey A Pleiss

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John Abelson

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Mario Blanco

http://www.w3.org/2001/XMLSchema#string

Mona Wood

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Pavithra Aravamudhan

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Tommaso Villa

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P2860

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

snRNA interactions at 5' and 3' splice sites monitored by photoactivated crosslinking in yeast spliceosomes

Global analysis of protein expression in yeast

Mechanical devices of the spliceosome: motors, clocks, springs, and things.

Composition and functional characterization of the yeast spliceosomal penta-snRNP.

The spliceosome: design principles of a dynamic RNP machine

Pre-mRNA splicing: awash in a sea of proteins

Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae

Yeast mRNA splicing in vitro

Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing

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504-512

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scholarly article

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1188018

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10.1038/NSMB.1767

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4

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17

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2010-03-21T00:00:00Z

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42372610

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20305654

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2881217

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