The spliceosome: a flexible, reversible macromolecular machine.
about
Phenotypic noise: effects of post-transcriptional regulatory processes affecting mRNADynamic integration of splicing within gene regulatory pathwaysRegulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanismsRNA helicases in splicingThe dharma of nonsense-mediated mRNA decay in mammalian cellsSelection for reduced translation costs at the intronic 5' end in fungiImpact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI miceStructural and functional analysis of the human spliceosomal DEAD-box helicase Prp28Mutations in the PQBP1 gene prevent its interaction with the spliceosomal protein U5-15 kDSplicing proofreading at 5' splice sites by ATPase Prp28p.Discovery of a splicing regulator required for cell cycle progressionInteraction between RNA helicase ROOT INITIATION DEFECTIVE 1 and GAMETOPHYTIC FACTOR 1 is involved in female gametophyte development in Arabidopsis.iSS-PseDNC: identifying splicing sites using pseudo dinucleotide composition.Biochemical defects in minor spliceosome function in the developmental disorder MOPD I.Aberrant RNA splicing and mutations in spliceosome complex in acute myeloid leukemia.Lariat intronic RNAs in the cytoplasm of Xenopus tropicalis oocytesGammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA.Stable intronic sequence RNA (sisRNA), a new class of noncoding RNA from the oocyte nucleus of Xenopus tropicalis.PRPF8 defects cause missplicing in myeloid malignancies.Transcriptomic characterization of cold acclimation in larval zebrafishModular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNALoss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.Mechanism of alternative splicing and its regulationExon skipping event prediction based on histone modifications.A conserved intronic U1 snRNP-binding sequence promotes trans-splicing in Drosophila.Role of six single nucleotide polymorphisms, risk factors in coronary disease, in OLR1 alternative splicingThe exosome controls alternative splicing by mediating the gene expression and assembly of the spliceosome complex.Nucleotide sequence composition adjacent to intronic splice sites improves splicing efficiency via its effect on pre-mRNA local folding in fungiThe network organization of protein interactions in the spliceosome is reproduced by the simple rules of food-web modelsNUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins.Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster.Multiscale methods for computational RNA enzymology.Bringing single-molecule spectroscopy to macromolecular protein complexes.Single-molecule colocalization FRET evidence that spliceosome activation precedes stable approach of 5' splice site and branch site.Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans.Single molecule analysis reveals reversible and irreversible steps during spliceosome activationFrac-seq reveals isoform-specific recruitment to polyribosomesRNA structure in splicing: An evolutionary perspectiveWhat have single-molecule studies taught us about gene expression?ARP2, a novel pro-apoptotic protein expressed in epithelial prostate cancer LNCaP cells and epithelial ovary CHO transformed cells.
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P2860
The spliceosome: a flexible, reversible macromolecular machine.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The spliceosome: a flexible, reversible macromolecular machine.
@ast
The spliceosome: a flexible, reversible macromolecular machine.
@en
type
label
The spliceosome: a flexible, reversible macromolecular machine.
@ast
The spliceosome: a flexible, reversible macromolecular machine.
@en
prefLabel
The spliceosome: a flexible, reversible macromolecular machine.
@ast
The spliceosome: a flexible, reversible macromolecular machine.
@en
P2860
P1476
The spliceosome: a flexible, reversible macromolecular machine.
@en
P2093
Aaron A Hoskins
Melissa J Moore
P2860
P304
P356
10.1016/J.TIBS.2012.02.009
P577
2012-04-03T00:00:00Z