about
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimersDifferential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathwaysMutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stabilityThe R1441C mutation of LRRK2 disrupts GTP hydrolysisPhosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylationRNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathwaysThe Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sitesThe Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylationStructure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPaseLeucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain
P50
Q24298093-70BA3FB7-B70E-48BB-8396-52372EB06889Q24299578-A51C860B-D40D-41C3-9ABB-38BEE0651DCDQ24299939-8B79D291-0D8D-4788-A74B-ECA4809C5681Q24303406-CB9080C8-0974-44D3-9689-A082AF80185CQ24309417-37CF4D64-450D-4EE3-8856-4E5E974A30C6Q24310126-58B4DC8F-0F43-42E1-A5B2-BDD99C27D6A3Q24313263-D4C9B40B-F988-4B6A-9E67-FD683CAF9DC8Q24313336-8806FE27-70ED-4CEB-A684-D247887B57C3Q24318533-9B317E16-9008-4F9B-BEBF-912E165CBFB8Q27649733-FDB73B8F-20A1-4C00-B00A-C7EC4FF78DC0Q28267434-6F46D531-01C9-4C13-A286-5021A5BAE227
P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Alexandra Beilina
@ast
Alexandra Beilina
@en
Alexandra Beilina
@es
Alexandra Beilina
@nl
Alexandra Beilina
@sl
type
label
Alexandra Beilina
@ast
Alexandra Beilina
@en
Alexandra Beilina
@es
Alexandra Beilina
@nl
Alexandra Beilina
@sl
prefLabel
Alexandra Beilina
@ast
Alexandra Beilina
@en
Alexandra Beilina
@es
Alexandra Beilina
@nl
Alexandra Beilina
@sl