The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.
about
Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machineStructural basis for autoinhibition and phosphorylation-dependent activation of c-CblRING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitinationProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesRINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesisFunctional diversity and structural disorder in the human ubiquitination pathwayEssentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformationTemporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiationCD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Tyrosine phosphorylation of the E3 ubiquitin ligase TRIM21 positively regulates interaction with IRF3 and hence TRIM21 activity.Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5.Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment.The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi ApparatusCIN85 phosphorylation is essential for EGFR ubiquitination and sorting into multivesicular bodies.Cbl-family proteins as regulators of cytoskeleton-dependent phenomena.Molecular mechanisms of SH2- and PTB-domain-containing proteins in receptor tyrosine kinase signaling.Cbl-family ubiquitin ligases and their recruitment of CIN85 are largely dispensable for epidermal growth factor receptor endocytosis.[Expressions of c-Cbl, Cbl-b and EGFR and its role of prognosis in NSCLC].Juvenile myelomonocytic leukemia due to a germline CBL Y371C mutation: 35-year follow-up of a large family.
P2860
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P2860
The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@ast
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@en
type
label
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@ast
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@en
prefLabel
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@ast
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@en
P2093
P2860
P356
P1476
The N terminus of Cbl-c regula ...... ubiquitin-conjugating enzyme.
@en
P2093
Marion M Nau
Nina Sivadasan-Nair
Philip E Ryan
Sarah Nicholas
Stanley Lipkowitz
P2860
P304
23687-23698
P356
10.1074/JBC.M109.091157
P407
P577
2010-06-04T00:00:00Z