Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.
about
ABL tyrosine kinases: evolution of function, regulation, and specificityRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsRole of ABL family kinases in cancer: from leukaemia to solid tumoursIdentification of small molecules that disrupt signaling between ABL and its positive regulator RIN1Constitutive Activity in an Ancestral Form of Abl Tyrosine Kinase.ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.Fear learning and extinction are linked to neuronal plasticity through Rin1 signaling.Direct interactions with the integrin β1 cytoplasmic tail activate the Abl2/Arg kinase.Tyrosine phosphorylation of RAS by ABL allosterically enhances effector bindingActivation of abl family kinases in solid tumors.RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.Structure and dynamic regulation of Abl kinases.The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking.RIN1 exhibits oncogenic property to suppress apoptosis and its aberrant accumulation associates with poor prognosis in melanoma.Changing the subcellular location of the oncoprotein Bcr-Abl using rationally designed capture motifsRIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25RIN1 regulates cell migration through RAB5 GTPases and ABL tyrosine kinases.A novel protein kinase D phosphorylation site in the tumor suppressor Rab interactor 1 is critical for coordination of cell migrationExpression and Production of SH2 Domain Proteins.Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum.Overexpression of RIN1 associates with tumor grade and progression in patients of bladder urothelial carcinoma.
P2860
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P2860
Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@ast
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@en
type
label
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@ast
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@en
prefLabel
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@ast
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@en
P2093
P2860
P356
P1476
Enhancement of ABL kinase cata ...... f other regulatory mechanisms.
@en
P2093
Anthony J Koleske
John Colicelli
Keith Q Tanis
Xiaoqing Cao
P2860
P304
31401-31407
P356
10.1074/JBC.M804002200
P407
P577
2008-09-16T00:00:00Z