The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains. - Wikidata - wikimedia - TriplyDB

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

http://www.wikidata.org/entity/Q30159822

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SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome Ubiquitylation-dependent downregulation of Nck regulates its functional activity Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Biochemical and Functional Insights into the Integrated Regulation of Innate Immune Cell Responses by Teleost Leukocyte Immune-Type Receptors Functions and regulation of circular dorsal ruffles The Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidance Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures The adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteria Nck adaptor proteins control the organization of neuronal circuits important for walking.SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells.Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins.Autoinhibitory interaction in the multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity.The adapter protein Nck: role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytes Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.Nck adapter proteins: functional versatility in T cells EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts.Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells.Recruitment of the adaptor protein Nck to PECAM-1 couples oxidative stress to canonical NF-κB signaling and inflammation.Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors Cellulose-bound peptide arrays: preparation and applications.Using genome-wide measurements for computational prediction of SH2-peptide interactions.Quantitative time-resolved phosphoproteomic analysis of mast cell signaling.SKAP2, a novel target of HSF4b, associates with NCK2/F-actin at membrane ruffles and regulates actin reorganization in lens cell.Integration of signaling and cytoskeletal remodeling by Nck in directional cell migration Enriching Traditional Protein-protein Interaction Networks with Alternative Conformations of Proteins.Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics.Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content.Structural insights into the intertwined dimer of fyn SH2 Teleost leukocyte immune-type receptors activate distinct phagocytic modes for target acquisition and engulfment.Downstream of tyrosine kinase 1 and 2 play opposing roles in CD200 receptor signaling.Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs.Nck deficiency is associated with delayed breast carcinoma progression and reduced metastasis.Proteomic Analysis of NCK1/2 Adaptors Uncovers Paralog-specific Interactions That Reveal a New Role for NCK2 in Cell Abscission During Cytokinesis

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P2860

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

http://www.wikidata.org/entity/Q30159822

description

2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

@ast

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

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type

label

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

@ast

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

@en

prefLabel

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

@ast

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains.

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

The phosphotyrosine peptide binding specificity of Nck1 and Nck2 Src homology 2 domains

@en

P2093

Antje C Findeis

http://www.w3.org/2001/XMLSchema#string

Dirk W Heinz

http://www.w3.org/2001/XMLSchema#string

Susanne Frese

http://www.w3.org/2001/XMLSchema#string

Tobias Marquardt

http://www.w3.org/2001/XMLSchema#string

Yvette S Roske

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck

Structural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domain

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment

Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

P304

18236-18245

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P31

scholarly article

P356

10.1074/JBC.M512917200

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P407

P433

26

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P478

281

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P50

Wolf-Dieter Schubert

Theresia Stradal

P577

2006-04-24T00:00:00Z

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P698

16636066

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