Protein folding kinetics beyond the phi value: using multiple amino acid substitutions to investigate the structure of the SH3 domain folding transition state.
about
Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein foldingDifferences in the folding transition state of ubiquitin indicated by phi and psi analysesOn the precision of experimentally determined protein folding rates and phi-valuesA residue in helical conformation in the native state adopts a β-strand conformation in the folding transition state despite its high and canonical Φ-value.Mutational investigation of protein folding transition states by Phi-value analysis and beyond: lessons from SH3 domain folding.The osmolyte trimethylamine-N-oxide stabilizes the Fyn SH3 domain without altering the structure of its folding transition state.Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR.Transition states for protein folding have native topologies despite high structural variability.Formation of the folding nucleus of an SH3 domain investigated by loosely coupled molecular dynamics simulations.Calculation of mutational free energy changes in transition states for protein folding.Structural and kinetic characterization of the simplified SH3 domain FP1.Assessing the effect of dynamics on the closed-loop protein-folding hypothesisDramatic acceleration of protein folding by stabilization of a nonnative backbone conformationInvestigation of an anomalously accelerating substitution in the folding of a prototypical two-state protein.Phi-value analysis and the nature of protein-folding transition statesEnergetics and mechanisms of folding and flipping the myristoyl switch in the {beta}-trefoil protein, hisactophilinHigh-Resolution Mapping of the Folding Transition State of a WW DomainComputational design of the Fyn SH3 domain with increased stability through optimization of surface charge charge interactionsSide chain burial and hydrophobic core packing in protein folding transition statesTesting the diffusing boundary model for the helix-coil transition in peptidesWhat lessons can be learned from studying the folding of homologous proteins?Dry molten globule intermediates and the mechanism of protein unfolding.Differential ordering of the protein backbone and side chains during protein folding revealed by site-specific recombinant infrared probes.Mutational analysis of different regions in the coxsackievirus 2B protein: requirements for homo-multimerization, membrane permeabilization, subcellular localization, and virus replication.Cofactor effects on the protein folding reaction: acceleration of alpha-lactalbumin refolding by metal ions.A "Link-Psi" strategy using crosslinking indicates that the folding transition state of ubiquitin is not very malleable.Quantifying the structural requirements of the folding transition state of protein A and other systems.Plasticity within the obligatory folding nucleus of an immunoglobulin-like domain.
P2860
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P2860
Protein folding kinetics beyond the phi value: using multiple amino acid substitutions to investigate the structure of the SH3 domain folding transition state.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Protein folding kinetics beyon ...... main folding transition state.
@ast
Protein folding kinetics beyon ...... main folding transition state.
@en
type
label
Protein folding kinetics beyon ...... main folding transition state.
@ast
Protein folding kinetics beyon ...... main folding transition state.
@en
prefLabel
Protein folding kinetics beyon ...... main folding transition state.
@ast
Protein folding kinetics beyon ...... main folding transition state.
@en
P1476
Protein folding kinetics beyon ...... main folding transition state.
@en
P2093
Alan R Davidson
Julian G B Northey
P304
P356
10.1016/S0022-2836(02)00445-X
P407
P577
2002-07-01T00:00:00Z