Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation
about
Protein folding: then and nowTheoretical and experimental demonstration of the importance of specific nonnative interactions in protein foldingNonnative Interactions in the FF Domain Folding Pathway from an Atomic Resolution Structure of a Sparsely Populated Intermediate: An NMR Relaxation Dispersion StudyElectrostatic effects in the folding of the SH3 domain of the c-Src tyrosine kinase: pH-dependence in 3D-domain swapping and amyloid formationMeasuring hydrogen exchange rates in invisible protein excited statesA residue in helical conformation in the native state adopts a β-strand conformation in the folding transition state despite its high and canonical Φ-value.Mutational investigation of protein folding transition states by Phi-value analysis and beyond: lessons from SH3 domain folding.The osmolyte trimethylamine-N-oxide stabilizes the Fyn SH3 domain without altering the structure of its folding transition state.Protein stabilization by specific binding of guanidinium to a functional arginine-binding surface on an SH3 domain.Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR.The folding mechanics of a knotted proteinbeta-Strand interactions at the domain interface critical for the stability of human lens gammaD-crystallinNonnative interactions in coupled folding and binding processes of intrinsically disordered proteins.The origin of nonmonotonic complex behavior and the effects of nonnative interactions on the diffusive properties of protein foldingChemical shift tensor - the heart of NMR: Insights into biological aspects of proteinsInvestigation of an anomalously accelerating substitution in the folding of a prototypical two-state protein.Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.Conserved prosegment residues stabilize a late-stage folding transition state of pepsin independently of ground states.Even with nonnative interactions, the updated folding transition states of the homologs Proteins G & L are extensive and similarObservation of sequential steps in the folding of intestinal fatty acid binding protein using a slow folding mutant and 19F NMR.The folding transition state of protein L is extensive with nonnative interactions (and not small and polarized).As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy.Nonnative interactions regulate folding and switching of myristoylated protein.Intermediates: ubiquitous species on folding energy landscapes?NMR spectroscopy brings invisible protein states into focus.Testing simplified proteins models of the hPin1 WW domain.Modulation of contact order effects in the two-state folding of stefins A and B.Chevron behavior and isostable enthalpic barriers in protein folding: successes and limitations of simple Gō-like modeling.Identification of fibril-like tertiary contacts in soluble monomeric α-synucleinThe mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints.A computational study of the effects of (13) C-(13) C scalar couplings on (13) C CEST NMR spectra: towards studies on a uniformly (13) C-labeled protein.The low populated folding intermediate of a mutant of the Fyn SH3 domain identified by a simple model.Probing slow timescale dynamics in proteins using methyl 1H CEST.Nonnative Energetic Frustrations in Protein Folding at Residual Level: A Simulation Study of Homologous Immunoglobulin-like β-Sandwich Proteins.
P2860
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P2860
Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Dramatic acceleration of prote ...... onnative backbone conformation
@ast
Dramatic acceleration of prote ...... onnative backbone conformation
@en
type
label
Dramatic acceleration of prote ...... onnative backbone conformation
@ast
Dramatic acceleration of prote ...... onnative backbone conformation
@en
prefLabel
Dramatic acceleration of prote ...... onnative backbone conformation
@ast
Dramatic acceleration of prote ...... onnative backbone conformation
@en
P2860
P50
P356
P1476
Dramatic acceleration of prote ...... onnative backbone conformation
@en
P2093
Alan R Davidson
Dmitry M Korzhnev
P2860
P304
P356
10.1073/PNAS.0400550101
P407
P577
2004-05-17T00:00:00Z