Folding mechanism of the alpha-subunit of tryptophan synthase, an alpha/beta barrel protein: global analysis highlights the interconversion of multiple native, intermediate, and unfolded forms through parallel channels.
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The role of a topologically conserved isoleucine in glutathione transferase structure, stability and functionThe nature of protein folding pathwaysTesting the role of chain connectivity on the stability and structure of dihydrofolate reductase from E. coli: fragment complementation and circular permutation reveal stable, alternatively folded formsThe folding free-energy surface of HIV-1 protease: insights into the thermodynamic basis for resistance to inhibitors.Zinc binding modulates the entire folding free energy surface of human Cu,Zn superoxide dismutase.Loop anchor modification causes the population of an alternative native state in an SH3-like domain.Folding kinetics of staphylococcal nuclease studied by tryptophan engineering and rapid mixing methods.The progressive development of structure and stability during the equilibrium folding of the alpha subunit of tryptophan synthase from Escherichia coli.Protein folding and misfolding: mechanism and principles.Mapping the structure of folding cores in TIM barrel proteins by hydrogen exchange mass spectrometry: the roles of motif and sequence for the indole-3-glycerol phosphate synthase from Sulfolobus solfataricus.Clusters of isoleucine, leucine, and valine side chains define cores of stability in high-energy states of globular proteins: Sequence determinants of structure and stability.Betaalpha-hairpin clamps brace betaalphabeta modules and can make substantive contributions to the stability of TIM barrel proteins.The relationship between chain connectivity and domain stability in the equilibrium and kinetic folding mechanisms of dihydrofolate reductase from E.coli.Characterization of THB1, a Chlamydomonas reinhardtii truncated hemoglobin: linkage to nitrogen metabolism and identification of lysine as the distal heme ligand.Analysis of kinetics using a hybrid maximum-entropy/nonlinear-least-squares method: application to protein folding.Equilibrium and kinetic folding pathways of a TIM barrel with a funneled energy landscapeChemical reactivity of Synechococcus sp. PCC 7002 and Synechocystis sp. PCC 6803 hemoglobins: covalent heme attachment and bishistidine coordination.The H2A-H2B dimeric kinetic intermediate is stabilized by widespread hydrophobic burial with few fully native interactions.A tightly packed hydrophobic cluster directs the formation of an off-pathway sub-millisecond folding intermediate in the alpha subunit of tryptophan synthase, a TIM barrel proteinElectron self-exchange and self-amplified posttranslational modification in the hemoglobins from Synechocystis sp. PCC 6803 and Synechococcus sp. PCC 7002.Protein-protein Förster resonance energy transfer analysis of nucleosome core particles containing H2A and H2A.Z.Identifying the structural boundaries of independent folding domains in the alpha subunit of tryptophan synthase, a beta/alpha barrel protein.Long-range side-chain-main-chain interactions play crucial roles in stabilizing the (betaalpha)8 barrel motif of the alpha subunit of tryptophan synthase.NMR analysis of partially folded states and persistent structure in the alpha subunit of tryptophan synthase: implications for the equilibrium folding mechanism of a 29-kDa TIM barrel protein.Equilibrium denaturation studies of the Escherichia coli factor for inversion stimulation: implications for in vivo function.Protein folding: independent unrelated pathways or predetermined pathway with optional errorsInterplay between drying and stability of a TIM barrel protein: a combined simulation-experimental study.Microsecond acquisition of heterogeneous structure in the folding of a TIM barrel protein.Proximal influences in two-on-two globins: effect of the Ala69Ser replacement on Synechocystis sp. PCC 6803 hemoglobinClusters of branched aliphatic side chains serve as cores of stability in the native state of the HisF TIM barrel protein.Enthalpic barriers dominate the folding and unfolding of the human Cu, Zn superoxide dismutase monomerDomain stabilities in protein kinase R (PKR): evidence for weak interdomain interactionsMetal deficiency increases aberrant hydrophobicity of mutant superoxide dismutases that cause amyotrophic lateral sclerosisFolding of the RNA recognition motif (RRM) domains of the amyotrophic lateral sclerosis (ALS)-linked protein TDP-43 reveals an intermediate stateWhat lessons can be learned from studying the folding of homologous proteins?A new general method for simultaneous fitting of temperature and concentration dependence of reaction rates yields kinetic and thermodynamic parameters for HIV reverse transcriptase specificity.Folding of proteins with a flavodoxin-like architecture.Topological frustration in beta alpha-repeat proteins: sequence diversity modulates the conserved folding mechanisms of alpha/beta/alpha sandwich proteins.Mutational studies uncover non-native structure in the dimeric kinetic intermediate of the H2A-H2B heterodimer.Analysis of monomeric and dimeric phosphorylated forms of protein kinase R.
P2860
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P2860
Folding mechanism of the alpha-subunit of tryptophan synthase, an alpha/beta barrel protein: global analysis highlights the interconversion of multiple native, intermediate, and unfolded forms through parallel channels.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Folding mechanism of the alpha ...... rms through parallel channels.
@ast
Folding mechanism of the alpha ...... rms through parallel channels.
@en
type
label
Folding mechanism of the alpha ...... rms through parallel channels.
@ast
Folding mechanism of the alpha ...... rms through parallel channels.
@en
prefLabel
Folding mechanism of the alpha ...... rms through parallel channels.
@ast
Folding mechanism of the alpha ...... rms through parallel channels.
@en
P2093
P356
P1433
P1476
Folding mechanism of the alpha ...... rms through parallel channels.
@en
P2093
Matthews CR
Zitzewitz JA
P304
P356
10.1021/BI982365Q
P407
P577
1999-01-01T00:00:00Z