Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents. - Wikidata - wikimedia - TriplyDB

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

http://www.wikidata.org/entity/Q30179416

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Inhibition of calpain prevents NMDA-induced cell death and beta-amyloid-induced synaptic dysfunction in hippocampal slice cultures Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease Amyloid-β Receptors: The Good, the Bad, and the Prion Protein Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer's disease immunotherapeutics α7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimum Ablation of Ca(V)2.1 voltage-gated Ca²⁺ channels in mouse forebrain generates multiple cognitive impairments A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2 Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes.Structural classification of toxic amyloid oligomers Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5 Modulation of microglial innate immunity in Alzheimer's disease by activation of peroxisome proliferator-activated receptor gamma.Cholesterol in the Pathogenesis of Alzheimer's, Parkinson's Diseases and Autism: Link to Synaptic Dysfunction Fibrillar oligomers nucleate the oligomerization of monomeric amyloid beta but do not seed fibril formation Homeostatic disinhibition in the aging brain and Alzheimer's disease Calcium signaling and amyloid toxicity in Alzheimer disease.Amyloid-beta-induced ion flux in artificial lipid bilayers and neuronal cells: resolving a controversy Polymorphic structures of Alzheimer's β-amyloid globulomers.Identification of novel short peptide inhibitors of soluble 37/48 kDa oligomers of amyloid β42.Mysterious oligomerization of the amyloidogenic proteins Effect of synthetic aβ peptide oligomers and fluorinated solvents on Kv1.3 channel properties and membrane conductance.β-amyloid oligomers and prion protein: Fatal attraction?Amyloid beta inhibits olfactory bulb activity and the ability to smell Neurotrophins enhance CaMKII activity and rescue amyloid-β-induced deficits in hippocampal synaptic plasticity.Timing-dependent septal cholinergic induction of dynamic hippocampal synaptic plasticity The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease.The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity.Soluble Aβ oligomer production and toxicity.VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.Ca(2+) channel currents of cortical neurons from pure and mixed cultures Spontaneous transmitter release is critical for the induction of long-term and intermediate-term facilitation in Aplysia Validation and Characterization of a Novel Peptide That Binds Monomeric and Aggregated β-Amyloid and Inhibits the Formation of Neurotoxic Oligomers.Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease Structural insights into Aβ42 oligomers using site-directed spin labeling Biomarkers for early diagnosis of Alzheimer disease: 'ALZheimer ASsociated gene'--a new blood biomarker?Multiple effects of β-amyloid on single excitatory synaptic connections in the PFC.

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Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

http://www.wikidata.org/entity/Q30179416

description

2008 nî lūn-bûn

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2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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Amyloid beta oligomers (A beta ...... of P/Q-type calcium currents.

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Amyloid beta oligomers (A beta ...... of P/Q-type calcium currents.

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Amyloid beta oligomers (A beta ...... of P/Q-type calcium currents.

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Amyloid beta oligomers (A beta ...... of P/Q-type calcium currents.

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JNEUROSCI.4771-07.2008

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Journal of Neuroscience

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Amyloid beta oligomers (A beta ...... n of P/Q-type calcium currents

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Alexander Lehmann

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Andreas Draguhn

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Christiane Grimm

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Claus Bruehl

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Gerhard Gross

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Hans Schoemaker

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Heinz Hillen

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Stefan Barghorn

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Ulrich Ebert

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Volker Nimmrich

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scholarly article

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10.1523/JNEUROSCI.4771-07.2008

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2008-01-01T00:00:00Z

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Calcium voltage-gated channel subunit alpha1 A

response to amyloid-beta

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6671006

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