Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts
about
Leupaxin is a novel LIM domain protein that forms a complex with PYK2The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent mannerDirect association of pp125FAK with paxillin, the focal adhesion-targeting mechanism of pp125FAKInteraction in vitro of the product of the c-Crk-II proto-oncogene with the insulin-like growth factor I receptorIntroduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinasesA novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent mannerCell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesionsMonocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteinsA novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytesAjuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner.Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells.Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.Hic-5-reduced cell spreading on fibronectin: competitive effects between paxillin and Hic-5 through interaction with focal adhesion kinasec-Abl kinase regulates the protein binding activity of c-CrkExpression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathwaysPaxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinaseDOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membraneIdentification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3GPaxillin comes of ageFocal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organizationIdentification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding.A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signalingThe focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxisStructure of the type III secretion and substrate-binding domain of Yersinia YopH phosphatasePhosphatidylinositol 3,4,5-trisphosphate directs association of Src homology 2-containing signaling proteins with gelsolinBCR/ABL-induced leukemogenesis causes phosphorylation of Hef1 and its association with CrklDirect association of protein-tyrosine phosphatase PTP-PEST with paxillinIntegrins regulate the association and phosphorylation of paxillin by c-AblPhosphorylation of CrkII adaptor protein at tyrosine 221 by epidermal growth factor receptorDirect binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinaseCRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cellsCytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogeneCbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillinRequirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesisMultiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillinInteraction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas
P2860
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P2860
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts
description
1993 nî lūn-bûn
@nan
1993 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Identification and characteriz ...... n CT10-transformed fibroblasts
@ast
Identification and characteriz ...... n CT10-transformed fibroblasts
@en
type
label
Identification and characteriz ...... n CT10-transformed fibroblasts
@ast
Identification and characteriz ...... n CT10-transformed fibroblasts
@en
prefLabel
Identification and characteriz ...... n CT10-transformed fibroblasts
@ast
Identification and characteriz ...... n CT10-transformed fibroblasts
@en
P2093
P2860
P356
P1476
Identification and characteriz ...... n CT10-transformed fibroblasts
@en
P2093
C Reichman
H Hanafusa
J E Fajardo
L C Cantley
S E Shoelson
Z Songyang
P2860
P304
P356
10.1128/MCB.13.8.4648
P407
P577
1993-08-01T00:00:00Z