Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis - Wikidata - wikimedia - TriplyDB

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

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Germline polymorphisms in SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer SPAL, a Rap-specific GTPase activating protein, is present in the NMDA receptor-PSD-95 complex in the hippocampus The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.Mechanism of the spatio-temporal regulation of Ras and Rap1.Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton The Rap1 guanine nucleotide exchange factor C3G is required for preservation of larval muscle integrity in Drosophila melanogaster Rap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formation Physical and functional interaction between Hck tyrosine kinase and guanine nucleotide exchange factor C3G results in apoptosis, which is independent of C3G catalytic domain Rap1 GTPases: an emerging role in the cardiovasculature Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells C3G regulates the size of the cerebral cortex neural precursor population The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I.C3G forms complexes with Bcr-Abl and p38α MAPK at the focal adhesions in chronic myeloid leukemia cells: implication in the regulation of leukemic cell adhesion.Signalling to actin: role of C3G, a multitasking guanine-nucleotide-exchange factor.Cardiovascular and craniofacial defects in Crk-null mice CrkL directs ASAP1 to peripheral focal adhesions.Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.An experimentally derived database of candidate Ras-interacting proteins.RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration.Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability Sipa1 is a candidate for underlying the metastasis efficiency modifier locus Mtes1.Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway.Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein Control of cell adhesion dynamics by Rap1 signaling.Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis.Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion T-cell receptor signaling to integrins.TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118.Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity.Ras-proximate-1 GTPase-activating protein and Rac2 may play pivotal roles in the initial development of myelodysplastic syndrome.Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila.

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Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

http://www.wikidata.org/entity/Q28343294

description

2001 nî lūn-bûn

@nan

2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հուլիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

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2001年论文

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name

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@ast

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@en

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@nl

type

label

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@ast

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@en

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@nl

prefLabel

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@ast

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@en

Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

@nl

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The EMBO Journal

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Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis

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A Ogura

http://www.w3.org/2001/XMLSchema#string

B J Mayer

http://www.w3.org/2001/XMLSchema#string

J Matsuda

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J Miyazaki

http://www.w3.org/2001/XMLSchema#string

K Ikuta

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K Kurokawa

http://www.w3.org/2001/XMLSchema#string

K Maki

http://www.w3.org/2001/XMLSchema#string

K Nagashima

http://www.w3.org/2001/XMLSchema#string

M Matsuda

http://www.w3.org/2001/XMLSchema#string

N Mochizuki

http://www.w3.org/2001/XMLSchema#string

P2860

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

A family of cAMP-binding proteins that directly activate Rap1

Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion

nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

Direct binding of p130(Cas) to the guanine nucleotide exchange factor C3G

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3333-41

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4718080

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10.1093/EMBOJ/20.13.3333

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13

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20

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11907754

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11432821

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125518

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