Vav: a potential link between tyrosine kinases and ras-like GTPases in hematopoietic cell signaling.
about
Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1Binding of Vav to Grb2 through dimerization of Src homology 3 domainsp95vav associates with the nuclear protein Ku-70The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain.Vav is necessary for prolactin-stimulated proliferation and is translocated into the nucleus of a T-cell line.Genes in the pX region of human T cell leukemia virus I influence Vav phosphorylation in T cells.The Src homology 2 domain of Vav is required for its compartmentation to the plasma membrane and activation of c-Jun NH(2)-terminal kinase 1.Nonhematopoietic cells are the primary source of bone marrow-derived lung epithelial cells.p95(vav) associates with the type I interferon (IFN) receptor and contributes to the antiproliferative effect of IFN-alpha in megakaryocytic cell lines.Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck.
P2860
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P2860
Vav: a potential link between tyrosine kinases and ras-like GTPases in hematopoietic cell signaling.
description
1993 nî lūn-bûn
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1993 թուականի Մարտին հրատարակուած գիտական յօդուած
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1993 թվականի մարտին հրատարակված գիտական հոդված
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1993年の論文
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1993年論文
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1993年論文
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1993年論文
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1993年論文
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1993年論文
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1993年论文
@wuu
name
Vav: a potential link between ...... hematopoietic cell signaling.
@ast
Vav: a potential link between ...... hematopoietic cell signaling.
@en
type
label
Vav: a potential link between ...... hematopoietic cell signaling.
@ast
Vav: a potential link between ...... hematopoietic cell signaling.
@en
prefLabel
Vav: a potential link between ...... hematopoietic cell signaling.
@ast
Vav: a potential link between ...... hematopoietic cell signaling.
@en
P2093
P2860
P356
P1433
P1476
Vav: a potential link between ...... hematopoietic cell signaling.
@en
P2093
P2860
P304
P356
10.1002/BIES.950150306
P407
P577
1993-03-01T00:00:00Z