Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.
about
Structure of the Q67H mutant of R67 dihydrofolate reductase-NADP+complex reveals a novel cofactor binding modeNovel crystallization conditions for tandem variant R67 DHFR yield a wild-type crystal structureCrystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrinTargeted and random bacterial gene disruption using a group II intron (targetron) vector containing a retrotransposition-activated selectable marker.Mechanistic studies of R67 dihydrofolate reductase. Effects of pH and an H62C mutation.The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major.Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active-site substitutionsSearching sequence space: two different approaches to dihydrofolate reductase catalysis.Construction of a dihydrofolate reductase-deficient mutant of Escherichia coli by gene replacement.Effect of multiple symmetries on the association of R67 DHFR subunits bearing interfacial complementing mutations.Trimethoprim resistance.Exploring the functional robustness of an enzyme by in vitro evolutionA novel antifolate resistance gene on the amplified H circle of Leishmania.Vibrational structure of dihydrofolate bound to R67 dihydrofolate reductase."Catch 222," the effects of symmetry on ligand binding and catalysis in R67 dihydrofolate reductase as determined by mutations at Tyr-69.Small Angle Neutron Scattering Studies of R67 Dihydrofolate Reductase, a Tetrameric Protein with Intrinsically Disordered N-Termini.Redesigning the Quaternary Structure of R67 Dihydrofolate Reductase
P2860
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P2860
Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67.
description
1986 nî lūn-bûn
@nan
1986 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
name
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@ast
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@en
type
label
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@ast
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@en
prefLabel
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@ast
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@en
P2093
P356
P1433
P1476
Crystal structure of a novel t ...... erichia coli by R-plasmid R67.
@en
P2093
P304
P356
10.1021/BI00363A005
P407
P577
1986-07-01T00:00:00Z