VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
about
A Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.LLOMe does not release cysteine cathepsins to the cytosol but inactivates them in transiently permeabilized lysosomes.Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases.C9orf72: At the intersection of lysosome cell biology and neurodegenerative disease.The Interplay of Cofactor Interactions and Post-translational Modifications in the Regulation of the AAA+ ATPase p97.Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies.The AAA+ ATPase p97, a cellular multitool.PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins.Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?Ubiquitin signaling and autophagy.Identification of Proteins Interacting with Ubiquitin Chains.Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures.Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.Removing the waste bags: how p97 drives autophagy of lysosomes.p62 filaments capture and present ubiquitinated cargos for autophagy.Autophagy balances inflammation in innate immunity.Causative Genes in Amyotrophic Lateral Sclerosis and Protein Degradation Pathways: a Link to Neurodegeneration.Cdc48 regulates a deubiquitylase cascade critical for mitochondrial fusion.AP-SWATH reveals direct involvement of VCP/p97 in integrated stress response signaling through facilitating CReP/PPP1R15B degradation.Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy
P2860
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P248
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P2860
VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy.
description
2016 nî lūn-bûn
@nan
2016 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@ast
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@en
type
label
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@ast
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@en
prefLabel
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@ast
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@en
P2093
P2860
P921
P356
P1433
P1476
VCP/p97 cooperates with YOD1, ...... ptured lysosomes by autophagy.
@en
P2093
Alina Dressler
Chrisovalantis Papadopoulos
Conrad C Weihl
Daniel Grum
Khalid Arhzaouy
Lisa Koerver
Monika Bug
Nina Schulze
Philipp Kirchner
Robert Poehler
P2860
P304
P356
10.15252/EMBJ.201695148
P407
P577
2016-10-17T00:00:00Z