The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone - Wikidata - wikimedia - TriplyDB

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

http://www.wikidata.org/entity/Q30299930

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Predictive computational modeling to define effective treatment strategies for bone metastatic prostate cancer.Transforming growth factor β as regulator of cancer stemness and metastasis Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer Long non-coding RNA NKILA inhibits migration and invasion of non-small cell lung cancer via NF-κB/Snail pathway Functional screen identifies kinases driving prostate cancer visceral and bone metastasis.Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.Clinicopathological study of 9 cases of prostate cancer involving the rectal wall.Ubiquitination and dynactin regulate TMEPAI lysosomal trafficking.Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone The origin of prostate metastases: emerging insights.CD271 determines migratory properties of melanoma cells.Surviving at a distance: organ specific metastasis.Pmepa1 induced by RANKL-p38 MAPK pathway has a novel role in osteoclastogenesis.Targeting metastasis.TGF-β Family Signaling in Tumor Suppression and Cancer Progression.Genomic characterization of liver metastases from colorectal cancer patients.Inhibition of KPNA4 attenuates prostate cancer metastasis.Molecular determinants of prostate cancer metastasis.An integrative model of prostate cancer interaction with the bone microenvironment.The Diverging Routes of BORIS and CTCF: An Interactomic and Phylogenomic Analysis.Current perspectives on bone metastases in castrate-resistant prostate cancer.Downregulation of miR‑19a‑3p promotes invasion, migration and bone metastasis via activating TGF‑β signaling in prostate cancer.TGF-β signaling in cancer metastasis.The molecular biology of prostate cancer: current understanding and clinical implications.Opposing roles of TGFβ and BMP signaling in prostate cancer development.Development of Novel Monoclonal Antibodies for Evaluation of Transmembrane Prostate Androgen-Induced Protein 1 (TMEPAI) Expression Patterns in Gastric Cancer.The TGF-β signalling negative regulator PICK1 represses prostate cancer metastasis to bone.The transmembrane protein TMEPAI induces myeloma cell apoptosis by promoting degradation of the c-Maf transcription factor.Activin A is a prominent autocrine regulator of hepatocyte growth arrest.PMEPA1 guards against TGF-β-mediated prostate cancer bone metastasis.Transcriptional downregulation of miR-133b by REST promotes prostate cancer metastasis to bone via activating TGF-β signaling.Genetics and biology of prostate cancer Peptide T7-modified polypeptide with disulfide bonds for targeted delivery of plasmid DNA for gene therapy of prostate cancer

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The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

http://www.wikidata.org/entity/Q30299930

description

2015 nî lūn-bûn

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2015 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2015 թվականի մայիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

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The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

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The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

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The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

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The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

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The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

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J.CCELL.2015.04.009

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P1476

The TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to Bone

@en

P2093

Clark D Wells

http://www.w3.org/2001/XMLSchema#string

Gregory A Clines

http://www.w3.org/2001/XMLSchema#string

Guanglong Jiang

http://www.w3.org/2001/XMLSchema#string

Holly W Walton

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Hun Soo Kim

http://www.w3.org/2001/XMLSchema#string

John M Chirgwin

http://www.w3.org/2001/XMLSchema#string

Khalid S Mohammad

http://www.w3.org/2001/XMLSchema#string

Maria Niewolna

http://www.w3.org/2001/XMLSchema#string

Patricia Juárez

http://www.w3.org/2001/XMLSchema#string

Xiang Hong Peng

http://www.w3.org/2001/XMLSchema#string

P2860

Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment.

A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling

PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression

Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

Latent bone metastasis in breast cancer tied to Src-dependent survival signals

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models

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809-821

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scholarly article

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10.1016/J.CCELL.2015.04.009

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6

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27

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Pierrick Fournier

Theresa A Guise

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2015-05-14T00:00:00Z

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25982816

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4464909

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