Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells. - Wikidata - wikimedia - TriplyDB

Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells.

Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells.

http://www.wikidata.org/entity/Q30308220

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Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNA Transcriptional Targeting in Cancer Gene Therapy Genomic approaches to identifying transcriptional regulators of osteoblast differentiation The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene The RUNX genes: gain or loss of function in cancer Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion Identification of the GATA factor TRPS1 as a repressor of the osteocalcin promoter.Advances in preclinical investigation of prostate cancer gene therapy.Prostate cancer and bone: the elective affinities.Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.Relationships between the Osteocalcin gene polymorphisms, serum osteocalcin levels, and hepatitis B virus-related hepatocellular carcinoma in a Chinese population Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter.The IGR-CaP1 xenograft model recapitulates mixed osteolytic/blastic bone lesions observed in metastatic prostate cancer Integrin αvβ3 and CD44 pathways in metastatic prostate cancer cells support osteoclastogenesis via a Runx2/Smad 5/receptor activator of NF-κB ligand signaling axis.Specific targeting of gene therapy to prostate cancer using a two-step transcriptional amplification system Endobiogeny: a global approach to systems biology (part 2 of 2)Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment.Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.Transcriptional repression of RUNX2 is associated with aggressive clinicopathological outcomes, whereas nuclear location of the protein is related to metastasis in prostate cancer.A Molecular View of Pathological Microcalcification in Breast Cancer.A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone.Assessment of an altered E1B promoter on the specificity and potency of triple-regulated conditionally replicating adenoviruses: implications for the generation of ideal m-CRAs.Association of core-binding factor β with the malignant phenotype of prostate and ovarian cancer cells.Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.An efficient construction of conditionally replicating adenoviruses that target tumor cells with multiple factors.Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.Notch signaling and ERK activation are important for the osteomimetic properties of prostate cancer bone metastatic cell lines.In vivo determination of vitamin d function using transgenic mice carrying a human osteocalcin luciferase reporter gene.RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53.In vivo bioluminescence imaging of cell differentiation in biomaterials: a platform for scaffold development.Osteomimicry: How the Seed Grows in the Soil.PTEN Loss Promotes Intratumoral Androgen Synthesis and Tumor Microenvironment Remodeling via Aberrant Activation of RUNX2 in Castration-Resistant Prostate Cancer.Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer.1alpha,25-dihydroxyvitamin D3 inhibits prostate cancer cell invasion via modulation of selective proteases.Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters.

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P2860

Regulation of human osteocalcin promoter in hormone-independent human prostate cancer cells.

http://www.wikidata.org/entity/Q30308220

description

2001 nî lūn-bûn

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2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի հոտեմբերին հրատարակված գիտական հոդված

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Regulation of human osteocalci ...... t human prostate cancer cells.

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Regulation of human osteocalci ...... t human prostate cancer cells.

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Regulation of human osteocalci ...... t human prostate cancer cells.

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Regulation of human osteocalci ...... t human prostate cancer cells.

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Regulation of human osteocalci ...... t human prostate cancer cells.

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Journal of Biological Chemistry

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Regulation of human osteocalci ...... t human prostate cancer cells.

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P2093

Ching-Hua Yeh

http://www.w3.org/2001/XMLSchema#string

Chinghai Kao

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Fan Yeung

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Jennifer J Westendorf

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Leland W K Chung

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Ruoxiang Wang

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Wai K Law

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Ye Zhang

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P2860

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

The distribution of secondary growths in cancer of the breast. 1889

Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment.

Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: a randomised phase II trial.

Why does bone matrix contain non-collagenous proteins? The possible roles of osteocalcin, osteonectin, osteopontin and bone sialoprotein in bone mineralisation and resorption.

Characterization of a gamma-carboxyglutamic acid-containing protein from bone

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.

Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene.

Impaired ossification in mice lacking the transcription factor Sp3.

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10.1074/JBC.M105947200

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277

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11667836

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11684680

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