Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.

Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.

Item
http://www.wikidata.org/entity/Q30308620
Interactome mapping suggests new mechanistic details underlying Alzheimer's diseaseHypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin.Meta-analyses of 8 polymorphisms associated with the risk of the Alzheimer's disease.The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies.Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity.Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.Hepcidin bound to α2-macroglobulin reduces ferroportin-1 expression and enhances its activity at reducing serum iron levels.Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons.Characterization of a novel positive transcription regulatory element that differentially regulates the alpha-2-macroglobulin gene in replicative senescence.Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling.α2-Macroglobulins: Structure and Function.Pregnancy Zone Protein is Increased in the Alzheimer's Disease Brain and Associates with Senile Plaques.A chemically modified preparation of alpha2-macroglobulin binds beta-amyloid peptide with increased affinity and inhibits Abeta cytotoxicity.Limited mutations in full-length tetrameric human alpha2-macroglobulin abrogate binding of platelet-derived growth factor-BB and transforming growth factor-beta1.Disruption of structural and functional integrity of alpha 2-macroglobulin by cathepsin E.
P2860

Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.

Item
http://www.wikidata.org/entity/Q30308620
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Distinct binding sites in the ...... id peptide and growth factors.
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Distinct binding sites in the ...... id peptide and growth factors.
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type
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Distinct binding sites in the ...... id peptide and growth factors.
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Distinct binding sites in the ...... id peptide and growth factors.
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Distinct binding sites in the ...... id peptide and growth factors.
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Distinct binding sites in the ...... id peptide and growth factors.
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P1433
P1476
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P1433
P1476
Distinct binding sites in the ...... id peptide and growth factors.
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698