Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling. - Wikidata - wikimedia - TriplyDB

Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling.

Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling.

http://www.wikidata.org/entity/Q39979231

about

LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages LDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous system Low density lipoprotein receptor-related protein 1 promotes anti-apoptotic signaling in neurons by activating Akt survival pathway.Low-Density Lipoprotein Receptor-Related Protein-1 Signaling in Angiogenesis.Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration.Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activities Ligation of prostate cancer cell surface GRP78 activates a proproliferative and antiapoptotic feedback loop: a role for secreted prostate-specific antigen.The unfolded protein response is a major mechanism by which LRP1 regulates Schwann cell survival after injury.CD91-dependent programming of T-helper cell responses following heat shock protein immunization.The NMDA receptor functions independently and as an LRP1 co-receptor to promote Schwann cell survival and migration.Kidney proteome changes provide evidence for a dynamic metabolism and regional redistribution of plasma proteins during torpor-arousal cycles of hibernation.Mesenchymal Stromal Cells Promote Axonal Outgrowth Alone and Synergistically with Astrocytes via tPA Regulation of cytokine expression by Schwann cells in response to α2-macroglobulin binding to LRP1.Low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cell signaling promotes axonal regeneration.Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons.LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia Neuroprotection and regeneration by extracellular metallothionein via lipoprotein-receptor-related proteins.LRP1 Regulates Retinal Angiogenesis by Inhibiting PARP-1 Activity and Endothelial Cell Proliferation.Ligand binding to LRP1 transactivates Trk receptors by a Src family kinase-dependent pathway.Identification of the protective mechanisms of Lactoferrin in the irradiated salivary gland.The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains.Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metalloproteinase Cascades.PAI-1: An Integrator of Cell Signaling and Migration.The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein.Ionotropic glutamate receptors activate cell signaling in response to glutamate in Schwann cells.Neuroserpin Attenuates H2O2-Induced Oxidative Stress in Hippocampal Neurons via AKT and BCL-2 Signaling Pathways.Neuron-derived transthyretin modulates astrocytic glycolysis in hormone-independent manner.LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation.Proteomic analysis of human epileptic neocortex predicts vascular and glial changes in epileptic regions.

P2860

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P2860

Molecular dissection of the human alpha2-macroglobulin subunit reveals domains with antagonistic activities in cell signaling.

http://www.wikidata.org/entity/Q39979231

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Molecular dissection of the hu ...... activities in cell signaling.

@en

Molecular dissection of the hu ...... activities in cell signaling.

@nl

type

label

Molecular dissection of the hu ...... activities in cell signaling.

@en

Molecular dissection of the hu ...... activities in cell signaling.

@nl

prefLabel

Molecular dissection of the hu ...... activities in cell signaling.

@en

Molecular dissection of the hu ...... activities in cell signaling.

@nl

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Journal of Biological Chemistry

P1476

Molecular dissection of the hu ...... c activities in cell signaling

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Steven L Gonias

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W Marie Campana

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Xiaoqing Li

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P2860

The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins

A modified human alpha 2-macroglobulin derivative that binds tumor necrosis factor-alpha and interleukin-1 beta with high affinity in vitro and reverses lipopolysaccharide toxicity in vivo in mice

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

Human alpha2-macroglobulin is composed of multiple domains, as predicted by homology with complement component C3

Domain structure of human alpha 2-macroglobulin. Characterization of a receptor-binding domain obtained by digestion with papain

Alpha-2 macroglobulin controls trophoblast positioning in mouse implantation sites

Cloning of complementary DNA for GAP-43, a neuronal growth-related protein

Apolipoprotein E-containing lipoproteins protect neurons from apoptosis via a signaling pathway involving low-density lipoprotein receptor-related protein-1

Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression

Identical or overlapping sequences in the primary structure of human alpha(2)-macroglobulin are responsible for the binding of nerve growth factor-beta, platelet-derived growth factor-BB, and transforming growth factor-beta.

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19904-19911

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10.1074/JBC.M801762200

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29

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283

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Elisabetta Mantuano

Gatambwa Mukandala

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2008-05-22T00:00:00Z

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5349900

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18499670

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2459272

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