Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma. - Wikidata - wikimedia - TriplyDB

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

http://www.wikidata.org/entity/Q30320562

about

Genetic and epigenetic alterations in pancreatic carcinogenesis PI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasms RASSF tumor suppressor gene family: biological functions and regulation Menin determines K-RAS proliferative outputs in endocrine cells PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration The Ras-association domain family (RASSF) members and their role in human tumourigenesis.Methylation associated inactivation of RASSF1A and its synergistic effect with activated K-Ras in nasopharyngeal carcinoma Aberrant DNA methyltransferase expression in pancreatic ductal adenocarcinoma development and progression.Epigenetics and pancreatic cancer: pathophysiology and novel treatment aspects Genomic Variations in Pancreatic Cancer and Potential Opportunities for Development of New Approaches for Diagnosis and Treatment.Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors.Comparison of the anti-cancer effect of Disulfiram and 5-Aza-CdR on pancreatic cancer cell line PANC-1 High-frequency aberrantly methylated targets in pancreatic adenocarcinoma identified via global DNA methylation analysis using methylCap-seq.Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis.Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer.Epigenetic regulation and role of metastasis suppressor genes in pancreatic ductal adenocarcinoma.Complex-based analysis of dysregulated cellular processes in cancer.Epigenetic silencing of erythropoietin in human cancers Effects of disulfiram on apoptosis in PANC-1 human pancreatic cancer cell line Identification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor gene.RASSF1 tumor suppressor gene in pancreatic ductal adenocarcinoma: correlation of expression, chromosomal status and epigenetic changes.Clinical utility of RASSF1A methylation in human malignancies.Advances in biomarker research for pancreatic cancer.3p21.3 tumor suppressor cluster: prospects for translational applications.DNA methylation: its role in cancer development and therapy.Genetic profiles in renal tumors.Molecular pathogenesis of pancreatic cancer and clinical perspectives.Epigenetic aspects on therapy development for gastroenteropancreatic neuroendocrine tumors.Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK.NETs: organ-related epigenetic derangements and potential clinical applications.Emergence of the Noncoding Cancer Genome: A Target of Genetic and Epigenetic Alterations.Effect of DNA methylation inhibitor on RASSF1A genes expression in non-small cell lung cancer cell line A549 and A549DDP.Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancer.APC alterations are frequently involved in the pathogenesis of acinar cell carcinoma of the pancreas, mainly through gene loss and promoter hypermethylation.Epigenetics of gastroenteropancreatic neuroendocrine tumors: A clinicopathologic perspective.The tumor suppressor RASSF10 is upregulated upon contact inhibition and frequently epigenetically silenced in cancer.Frequent promoter methylation and gene silencing of CDH13 in pancreatic cancer.Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer.Aberrant methylation of the negative regulators RASSFIA, SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia.Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis.

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Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

http://www.wikidata.org/entity/Q30320562

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

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name

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@ast

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@en

type

label

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@ast

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@en

prefLabel

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@ast

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@en

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Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma.

@en

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Bernhard O Boehm

http://www.w3.org/2001/XMLSchema#string

Cuong Hoang-Vu

http://www.w3.org/2001/XMLSchema#string

Gerd P Pfeifer

http://www.w3.org/2001/XMLSchema#string

Limin Liu

http://www.w3.org/2001/XMLSchema#string

Noreen Otto

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Oliver Gimm

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Reinhard Dammann

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Undraga Schagdarsurengin

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P2860

Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis

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3806-3812

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scholarly article

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10.1038/SJ.ONC.1206582

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22

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10712613

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1034914764

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12802288

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