about
Structural, kinetic and chemical mechanism of isocitrate dehydrogenase-1 from Mycobacterium tuberculosisA flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolismA balancing act: efflux/influx in mycobacterial drug resistanceTranslating basic science insight into public health action for multidrug- and extensively drug-resistant tuberculosisStrategies for potentiation of ethionamide and folate antagonists against Mycobacterium tuberculosis3‘-Phosphoadenosine-5‘-phosphosulfate Reductase in Complex with Thioredoxin: A Structural Snapshot in the Catalytic Cycle † , ‡Mycobacterium tuberculosis CYP130: CRYSTAL STRUCTURE, BIOPHYSICAL CHARACTERIZATION, AND INTERACTIONS WITH ANTIFUNGAL AZOLE DRUGSStructural Basis for Catalysis of a Tetrameric Class IIa Fructose 1,6-Bisphosphate Aldolase from Mycobacterium tuberculosisStructural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation.Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversityPrioritizing genomic drug targets in pathogens: application to Mycobacterium tuberculosisCharacterization of mRNA interferases from Mycobacterium tuberculosisACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteriaA gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophagesKinetic mechanism determination and analysis of metal requirement of dehydroquinate synthase from Mycobacterium tuberculosis H37Rv: an essential step in the function-based rational design of anti-TB drugsBiochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosisPhoY2 but not PhoY1 is the PhoU homologue involved in persisters in Mycobacterium tuberculosisEnhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian modelsWhole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patientsLooking back to the future: predicting in vivo efficacy of small molecules versus Mycobacterium tuberculosisOpen Drug Discovery Teams: A Chemistry Mobile App for Collaboration[Au]/[Ag]-catalysed expedient synthesis of branched heneicosafuranosyl arabinogalactan motif of Mycobacterium tuberculosis cell wallMechanisms of Pyrazinamide Action and ResistanceEmerging Approaches to Tuberculosis Drug Development: At Home in the Metabolome.Tuberculosis Drug Development: History and Evolution of the Mechanism-Based Paradigm.Fusing dual-event data sets for Mycobacterium tuberculosis machine learning models and their evaluation.Are bigger data sets better for machine learning? Fusing single-point and dual-event dose response data for Mycobacterium tuberculosisStructural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis.Identification of gene targets against dormant phase Mycobacterium tuberculosis infectionsTargeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents.Safety and immunogenicity of a new tuberculosis vaccine, MVA85A, in Mycobacterium tuberculosis-infected individuals.A peptide fragment from the human COX3 protein disrupts association of Mycobacterium tuberculosis virulence proteins ESAT-6 and CFP10, inhibits mycobacterial growth and mounts protective immune responseValidating new tuberculosis computational models with public whole cell screening aerobic activity datasets.Combinatorially-generated library of 6-fluoroquinolone analogs as potential novel antitubercular agents: a chemometric and molecular modeling assessment.Iron and thiols as two major players in carcinogenesis: friends or foes?Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery.Protein-protein interaction networks suggest different targets have different propensities for triggering drug resistance.Exploring anti-TB leads from natural products library originated from marine microbes and medicinal plants.Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.Pathway-selective sensitization of Mycobacterium tuberculosis for target-based whole-cell screening
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The magic bullets and tuberculosis drug targets.
@ast
The magic bullets and tuberculosis drug targets.
@en
type
label
The magic bullets and tuberculosis drug targets.
@ast
The magic bullets and tuberculosis drug targets.
@en
prefLabel
The magic bullets and tuberculosis drug targets.
@ast
The magic bullets and tuberculosis drug targets.
@en
P1476
The magic bullets and tuberculosis drug targets.
@en
P2093
Ying Zhang
P304
P356
10.1146/ANNUREV.PHARMTOX.45.120403.100120
P577
2005-01-01T00:00:00Z