Progression of inner ear pathology in Ames waltzer mice and the role of protocadherin 15 in hair cell development.
about
Clarin-1, encoded by the Usher Syndrome III causative gene, forms a membranous microdomain: possible role of clarin-1 in organizing the actin cytoskeletonDevelopment and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.A new spontaneous mutation in the mouse protocadherin 15 gene.Cadherins and mechanotransduction by hair cellsUsher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activationRegulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domainFCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro.The mechanosensory structure of the hair cell requires clarin-1, a protein encoded by Usher syndrome III causative geneA mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.Nerve maintenance and regeneration in the damaged cochlea.Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleaeDeafness and retinal degeneration in a novel USH1C knock-in mouse modelSupporting cell characteristics in long-deafened aged mouse earsThe micromachinery of mechanotransduction in hair cells.Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.An ENU-induced mutation of Cdh23 causes congenital hearing loss, but no vestibular dysfunction, in mice.Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells.The cuticular plate: a riddle, wrapped in a mystery, inside a hair cell.Severe streptomycin ototoxicity in the mouse utricle leads to a flat epithelium but the peripheral neural degeneration is delayed.
P2860
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P2860
Progression of inner ear pathology in Ames waltzer mice and the role of protocadherin 15 in hair cell development.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Progression of inner ear patho ...... n 15 in hair cell development.
@ast
Progression of inner ear patho ...... n 15 in hair cell development.
@en
type
label
Progression of inner ear patho ...... n 15 in hair cell development.
@ast
Progression of inner ear patho ...... n 15 in hair cell development.
@en
prefLabel
Progression of inner ear patho ...... n 15 in hair cell development.
@ast
Progression of inner ear patho ...... n 15 in hair cell development.
@en
P2093
P2860
P1433
P1476
Progression of inner ear patho ...... n 15 in hair cell development.
@en
P2093
Charles G Wright
Karen S Pawlowski
Kumar N Alagramam
Yayoi S Kikkawa
P2860
P2888
P356
10.1007/S10162-005-0024-5
P577
2006-01-12T00:00:00Z
P5875
P6179
1037829309