18O labeling method for identification and quantification of succinimide in proteins.
about
Structural Investigation of a Phosphorylation-Catalyzed, Isoaspartate-Free, Protein Succinimide: Crystallographic Structure of Post-Succinimide His15Asp Histidine-Containing Protein † ‡Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperaturesStructure-based prediction of asparagine and aspartate degradation sites in antibody variable regionsEffect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody.Top-down study of β2-microglobulin deamidationA new tool for monoclonal antibody analysis: application of IdeS proteolysis in IgG domain-specific characterization.Chromatographic analysis of the acidic and basic species of recombinant monoclonal antibodies.An 18O-labeling assisted LC/MS method for assignment of aspartyl/isoaspartyl products from Asn deamidation and Asp isomerization in proteinsDifferentiating N-terminal aspartic and isoaspartic acid residues in peptides.Detection and quantitation of succinimide in intact protein via hydrazine trapping and chemical derivatization.Acetic acid can catalyze succinimide formation from aspartic acid residues by a concerted bond reorganization mechanism: a computational study.Comparison of the in vitro and in vivo stability of a succinimide intermediate observed on a therapeutic IgG1 molecule.Analysis of isoaspartic Acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry.In-Source Decay Characterization of Isoaspartate and β-Peptides.Use of 18O labels to monitor deamidation during protein and peptide sample processing.Mass spectrometric distinction of in-source and in-solution pyroglutamate and succinimide in proteins: a case study on rhG-CSF.Characterization of the isomerization products of aspartate residues at two different sites in a monoclonal antibody.Quantification of in vivo site-specific Asp isomerization and Asn deamidation of mAbs in animal serum using IP-LC-MS.
P2860
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P2860
18O labeling method for identification and quantification of succinimide in proteins.
description
2007 nî lūn-bûn
@nan
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
18O labeling method for identification and quantification of succinimide in proteins.
@ast
18O labeling method for identification and quantification of succinimide in proteins.
@en
type
label
18O labeling method for identification and quantification of succinimide in proteins.
@ast
18O labeling method for identification and quantification of succinimide in proteins.
@en
prefLabel
18O labeling method for identification and quantification of succinimide in proteins.
@ast
18O labeling method for identification and quantification of succinimide in proteins.
@en
P2093
P356
P1433
P1476
18O labeling method for identification and quantification of succinimide in proteins.
@en
P2093
Dirk Chelius
Grace C Chu
Jaby Jacob
Pavel V Bondarenko
P304
P356
10.1021/AC0617870
P407
P577
2007-02-22T00:00:00Z