Structure and phospholipase function of peroxiredoxin 6: identification of the catalytic triad and its role in phospholipid substrate binding.
about
Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genesIntracellular targeting of peroxiredoxin 6 to lysosomal organelles requires MAPK activity and binding to 14-3-3εThe serpentine path to a novel mechanism-based inhibitor of acute inflammatory lung injuryQuantitative redox biology: an approach to understand the role of reactive species in defining the cellular redox environmentMass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosisPeroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration.Peroxiredoxins and Redox Signaling in Plants.Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposurePeroxiredoxin VI oxidation in cerebrospinal fluid correlates with traumatic brain injury outcomePeroxiredoxin 6 differentially regulates acute and chronic cigarette smoke–mediated lung inflammatory response and injury.Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.Lentivirus-mediated inhibition of tumour necrosis factor-α improves motor function associated with PRDX6 in spinal cord contusion ratsPeroxiredoxin 6 interferes with TRAIL-induced death-inducing signaling complex formation by binding to death effector domain caspase.Solution structure of the reduced form of human peroxiredoxin-6 elucidated using zero-length chemical cross-linking and homology modelling.Delineating the role of alterations in lipid metabolism to the pathogenesis of inherited skeletal and cardiac muscle disorders: Thematic Review Series: Genetics of Human Lipid Diseases.The roles of peroxidase and phospholipase A2 activities of peroxiredoxin 6 in protecting pulmonary microvascular endothelial cells against peroxidative stress.Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.Peroxiredoxin 6 from the Antarctic emerald rockcod: molecular characterization of its response to warming.Probing structures of large protein complexes using zero-length cross-linking.Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein.Allelic variants of glutathione S-transferase P1-1 differentially mediate the peroxidase function of peroxiredoxin VI and alter membrane lipid peroxidation.A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6Peroxiredoxin 6 homodimerization and heterodimerization with glutathione S-transferase pi are required for its peroxidase but not phospholipase A2 activity.Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice.Mutation of Serine 32 to Threonine in Peroxiredoxin 6 Preserves Its Structure and Enzymatic Function but Abolishes Its Trafficking to Lamellar Bodies.Redox signals in wound healingThe emerging role of group VI calcium-independent phospholipase A2 in releasing docosahexaenoic acid from brain phospholipids.Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice.Mitogen-activated protein kinase-mediated phosphorylation of peroxiredoxin 6 regulates its phospholipase A(2) activity.Identification of the amino acid sequence that targets peroxiredoxin 6 to lysosome-like structures of lung epithelial cells.The Antioxidant Peroxiredoxin 6 (Prdx6) Exhibits Different Profiles in the Livers of Seawater- and Fresh Water-Acclimated Milkfish, Chanos chanos, upon Hypothermal Challenge.Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities.Chronic Effects of Ethanol and/or Darunavir/Ritonavir on U937 Monocytic Cells: Regulation of Cytochrome P450 and Antioxidant Enzymes, Oxidative Stress, and CytotoxicityCritical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stressPeroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling.Lactate detection in inducible and orthotopic Her2/neu mammary gland tumours in mouse modelsPhox activity of differentiated PLB-985 cells is enhanced, in an agonist specific manner, by the PLA2 activity of Prdx6-PLA2.Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities.Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response elementPeroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes.
P2860
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P2860
Structure and phospholipase function of peroxiredoxin 6: identification of the catalytic triad and its role in phospholipid substrate binding.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Structure and phospholipase fu ...... hospholipid substrate binding.
@ast
Structure and phospholipase fu ...... hospholipid substrate binding.
@en
type
label
Structure and phospholipase fu ...... hospholipid substrate binding.
@ast
Structure and phospholipase fu ...... hospholipid substrate binding.
@en
prefLabel
Structure and phospholipase fu ...... hospholipid substrate binding.
@ast
Structure and phospholipase fu ...... hospholipid substrate binding.
@en
P2093
P2860
P1476
Structure and phospholipase fu ...... hospholipid substrate binding.
@en
P2093
Aron B Fisher
Konda S Reddy
Sheldon I Feinstein
Tea Shuvaeva
Yefim Manevich
P2860
P304
P356
10.1194/JLR.M700299-JLR200
P577
2007-07-24T00:00:00Z