Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.
about
Functional interaction of glutathione S-transferase pi and peroxiredoxin 6 in intact cellsMultiple Roles of Peroxiredoxins in InflammationStop the flow: a paradigm for cell signaling mediated by reactive oxygen species in the pulmonary endotheliumThe serpentine path to a novel mechanism-based inhibitor of acute inflammatory lung injuryRedox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cellsRegulation of signal transduction by reactive oxygen species in the cardiovascular systemAnti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6p67(phox) terminates the phospholipase A(2)-derived signal for activation of NADPH oxidase (NOX2)Peroxiredoxin 6 (Prdx6) supports NADPH oxidase1 (Nox1)-based superoxide generation and cell migration.Arachidonic acid induces direct interaction of the p67(phox)-Rac complex with the phagocyte oxidase Nox2, leading to superoxide production.Shear stress-related mechanosignaling with lung ischemia: lessons from basic research can inform lung transplantation.Loss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development.The roles of peroxidase and phospholipase A2 activities of peroxiredoxin 6 in protecting pulmonary microvascular endothelial cells against peroxidative stress.Protein glutathionylation in the regulation of peroxiredoxins: a family of thiol-specific peroxidases that function as antioxidants, molecular chaperones, and signal modulators.Redox regulation of mammalian sperm capacitation.Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS.Peroxiredoxin 1 suppresses apoptosis via regulation of the apoptosis signal-regulating kinase 1 signaling pathway in human oral leukoplakiaRegulation of alveolar macrophage p40phox: hierarchy of activating kinases and their inhibition by PGE2Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD.Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein.Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4.Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo.Inactivation of Peroxiredoxin 6 by the Pla Protease of Yersinia pestis.Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia.A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung.Proteomic analysis of the supernatant of red blood cell units: the effects of storage and leucoreductionPECAM-1 and caveolae form the mechanosensing complex necessary for NOX2 activation and angiogenic signaling with stopped flow in pulmonary endothelium.Quantitative HDL Proteomics Identifies Peroxiredoxin-6 as a Biomarker of Human Abdominal Aortic Aneurysm.Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2).The accumulation of lipids and proteins during red blood cell storage: the roles of leucoreduction and experimental filtration.Reactive oxygen species and endothelial function--role of nitric oxide synthase uncoupling and Nox family nicotinamide adenine dinucleotide phosphate oxidases.Reactive oxygen species as therapeutic targets in pulmonary hypertension.S-glutathionylation of ion channels: insights into the regulation of channel functions, thiol modification crosstalk, and mechanosensingMechanotransduction in the endothelium: role of membrane proteins and reactive oxygen species in sensing, transduction, and transmission of the signal with altered blood flowThe impact of thiol peroxidases on redox regulation.Binding sites for interaction of peroxiredoxin 6 with surfactant protein A.Redox homeostasis and age-related deficits in neuromuscular integrity and function.Microglia antioxidant systems and redox signalling.ExoU-induced redox imbalance and oxidative stress in airway epithelial cells during Pseudomonas aeruginosa pneumosepsis.Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling.
P2860
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P2860
Peroxiredoxin 6 phosphorylation and subsequent phospholipase A2 activity are required for agonist-mediated activation of NADPH oxidase in mouse pulmonary microvascular endothelium and alveolar macrophages.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@ast
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@en
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@nl
type
label
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@ast
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@en
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@nl
prefLabel
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@ast
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@en
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@nl
P2093
P2860
P356
P1476
Peroxiredoxin 6 phosphorylatio ...... lium and alveolar macrophages.
@en
P2093
Aron B Fisher
Chandra Dodia
David Speicher
Elena Sorokina
Kris Debolt
Shampa Chatterjee
Sheldon I Feinstein
Yu-Chin Lien
P2860
P304
11696-11706
P356
10.1074/JBC.M110.206623
P407
P577
2011-01-24T00:00:00Z