about
Systems medicine: the future of medical genomics and healthcareChanging genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationshipsThree-dimensional reconstruction of protein networks provides insight into human genetic diseaseCancer missense mutations alter binding properties of proteins and their interaction networksCollaboratively charting the gene-to-phenotype network of human congenital heart defectsImpaired protein stability and nuclear localization of NOBOX variants associated with premature ovarian insufficiencyInteractome networks and human diseaseDomain-mediated protein interaction prediction: From genome to network.Computational identification of pathogenic associated nsSNPs and its structural impact in UROD gene: a molecular dynamics approach.Identifying mutation specific cancer pathways using a structurally resolved protein interaction network.Modulating protein-protein interactions with small molecules: the importance of binding hotspots.Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition.Prediction of cancer proteins by integrating protein interaction, domain frequency, and domain interaction data using machine learning algorithms.The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastomaDosage sensitivity shapes the evolution of copy-number varied regions.High-resolution network biology: connecting sequence with function.Mechanisms of protein oligomerization, the critical role of insertions and deletions in maintaining different oligomeric statesThe structural network of Interleukin-10 and its implications in inflammation and cancerMutation@A Glance: an integrative web application for analysing mutations from human genetic diseases.Evolution: a guide to perturb protein function and networksBiophysics of protein evolution and evolutionary protein biophysicsOncogenic potential is related to activating effect of cancer single and double somatic mutations in receptor tyrosine kinasesDisease-related mutations predicted to impact protein function.Schizophrenia interactome with 504 novel protein-protein interactionsComparison of modules of wild type and mutant Huntingtin and TP53 protein interaction networks: implications in biological processes and functions.Identification of residues in the N-terminal PAS domains important for dimerization of Arnt and AhR.Signatures of pleiotropy, economy and convergent evolution in a domain-resolved map of human-virus protein-protein interaction networks.A systems biology investigation of neurodegenerative dementia reveals a pivotal role of autophagy.IRView: a database and viewer for protein interacting regions.Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease.Mechanisms of Calmodulin Regulation of Different Isoforms of Kv7.4 K+ ChannelsHierarchical approaches for systems modeling in cardiac development.INstruct: a database of high-quality 3D structurally resolved protein interactome networksDissecting disease inheritance modes in a three-dimensional protein network challenges the "guilt-by-association" principle.VisANT: an integrative framework for networks in systems biology.A network medicine approach to human disease.From protein interaction networks to novel therapeutic strategies.Interactome mapping for analysis of complex phenotypes: insights from benchmarking binary interaction assays.Protein interaction networks in medicine and disease.Exploring mechanisms of human disease through structurally resolved protein interactome networks.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Protein interactions in human genetic diseases.
@ast
Protein interactions in human genetic diseases.
@en
type
label
Protein interactions in human genetic diseases.
@ast
Protein interactions in human genetic diseases.
@en
prefLabel
Protein interactions in human genetic diseases.
@ast
Protein interactions in human genetic diseases.
@en
P2860
P356
P1433
P1476
Protein interactions in human genetic diseases.
@en
P2860
P2888
P356
10.1186/GB-2008-9-1-R9
P577
2008-01-16T00:00:00Z
P5875
P6179
1036478548