Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis.
about
KRIT1 regulates the homeostasis of intracellular reactive oxygen speciesPhox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPasesStructural basis of the junctional anchorage of the cerebral cavernous malformations complexStructural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1)Identification of the Kelch family protein Nd1-L as a novel molecular interactor of KRIT1Phosphorylation sites in the cerebral cavernous malformations complexRecent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction.A mechanism of Rap1-induced stabilization of endothelial cell--cell junctions.Cerebral cavernous malformation proteins at a glance.Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology.Cerebral cavernous malformations: from molecular pathogenesis to genetic counselling and clinical management.Genetic and cellular basis of cerebral cavernous malformations: implications for clinical management.Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction.CCM1 and the second life of proteins in adhesion complexes.Unexpected distribution of KRIT1 inside the nucleus: new insight in a complex molecular pathway.KRIT1 loss of function causes a ROS-dependent upregulation of c-JunmiR-21 coordinates tumor growth and modulates KRIT1 levels.Rap1 signaling in endothelial barrier control.PX-FERM proteins: A link between endosomal trafficking and signaling?Nuclear Localization of Integrin Cytoplasmic Domain-associated Protein-1 (ICAP1) Influences β1 Integrin Activation and Recruits Krev/Interaction Trapped-1 (KRIT1) to the Nucleus.Novel loss of function mutation in KRIT1/CCM1 is associated with distinctly progressive cerebral and spinal cavernous malformations after radiochemotherapy for intracranial malignant germ cell tumor.Mutation analysis of CCM1, CCM2 and CCM3 genes in a cohort of Italian patients with cerebral cavernous malformation.
P2860
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P2860
Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural and functional diff ...... nderstanding CCM pathogenesis.
@ast
Structural and functional diff ...... nderstanding CCM pathogenesis.
@en
type
label
Structural and functional diff ...... nderstanding CCM pathogenesis.
@ast
Structural and functional diff ...... nderstanding CCM pathogenesis.
@en
prefLabel
Structural and functional diff ...... nderstanding CCM pathogenesis.
@ast
Structural and functional diff ...... nderstanding CCM pathogenesis.
@en
P2093
P50
P1476
Structural and functional diff ...... understanding CCM pathogenesis
@en
P2093
Elisa De Luca
Fiorella Balzac
Floriana Francalanci
Francesco Sgrò
Luca Goitre
Marco Marino
Maria Avolio
Paolo Guazzi
Valeria Menchise
P304
P356
10.1016/J.YEXCR.2008.10.006
P407
P577
2008-10-21T00:00:00Z